Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FAHD2BFumarylacetoacetate hydrolase domain-containing protein 2B; May have hydrolase activity. (314 aa)    
Predicted Functional Partners:
FAHD2A
Fumarylacetoacetate hydrolase domain-containing protein 2A; May have hydrolase activity.
  
 
0.999
BOLA3
BolA-like protein 3; Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins. Probably acts together with NFU1 ; Belongs to the BolA/IbaG family.
   
 
 0.800
FAM178B
Protein FAM178B; Family with sequence similarity 178 member B.
   
  
 0.657
HGD
Homogentisate 1,2-dioxygenase.
  
 
 0.628
ANKRD39
Ankyrin repeat domain 39; Belongs to the ANKRD39 family.
   
  
 0.584
ITPRIPL1
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.
    
 
 0.571
ANKRD36
Ankyrin repeat domain-containing protein 36A; Ankyrin repeat domain 36.
      
 0.550
CNNM3
Metal transporter CNNM3; Probable metal transporter; Belongs to the ACDP family.
   
  
 0.503
VARS1
Valine--tRNA ligase; valyl-tRNA synthetase 1; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.493
LMAN2L
VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53.
   
  
 0.467
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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