| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DCHS1 | FAT4 | ENSP00000299441 | ENSP00000377862 | Protocadherin-16; Calcium-dependent cell-adhesion protein. Mediates functions in neuroprogenitor cell proliferation and differentiation. In the heart, has a critical role for proper morphogenesis of the mitral valve, acting in the regulation of cell migration involved in valve formation. | Protocadherin Fat 4; Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). | 0.930 |
| DCHS1 | FJX1 | ENSP00000299441 | ENSP00000400223 | Protocadherin-16; Calcium-dependent cell-adhesion protein. Mediates functions in neuroprogenitor cell proliferation and differentiation. In the heart, has a critical role for proper morphogenesis of the mitral valve, acting in the regulation of cell migration involved in valve formation. | Four-jointed box protein 1; Acts as an inhibitor of dendrite extension and branching. Belongs to the FJX1/FJ family. | 0.667 |
| FAT4 | DCHS1 | ENSP00000377862 | ENSP00000299441 | Protocadherin Fat 4; Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). | Protocadherin-16; Calcium-dependent cell-adhesion protein. Mediates functions in neuroprogenitor cell proliferation and differentiation. In the heart, has a critical role for proper morphogenesis of the mitral valve, acting in the regulation of cell migration involved in valve formation. | 0.930 |
| FAT4 | FJX1 | ENSP00000377862 | ENSP00000400223 | Protocadherin Fat 4; Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). | Four-jointed box protein 1; Acts as an inhibitor of dendrite extension and branching. Belongs to the FJX1/FJ family. | 0.926 |
| FAT4 | LAMC1 | ENSP00000377862 | ENSP00000258341 | Protocadherin Fat 4; Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). | Laminin subunit gamma-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | 0.679 |
| FAT4 | MUC16 | ENSP00000377862 | ENSP00000381008 | Protocadherin Fat 4; Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). | Mucin-16; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. | 0.622 |
| FAT4 | NXPH2 | ENSP00000377862 | ENSP00000272641 | Protocadherin Fat 4; Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). | Neurexophilin-2; May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors. Belongs to the neurexophilin family. | 0.610 |
| FAT4 | PCLO | ENSP00000377862 | ENSP00000334319 | Protocadherin Fat 4; Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). | Protein piccolo; Scaffold protein of the presynaptic cytomatrix at the active zone (CAZ) which is the place in the synapse where neurotransmitter is released (By similarity). After synthesis, participates in the formation of Golgi-derived membranous organelles termed Piccolo-Bassoon transport vesicles (PTVs) that are transported along axons to sites of nascent synaptic contacts (By similarity). At the presynaptic active zone, regulates the spatial organization of synaptic vesicle cluster, the protein complexes that execute membrane fusion and compensatory endocytosis (By similarity). O [...] | 0.616 |
| FAT4 | SPTBN1 | ENSP00000377862 | ENSP00000349259 | Protocadherin Fat 4; Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). | Spectrin beta chain, non-erythrocytic 1; Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. | 0.591 |
| FAT4 | SYNE1 | ENSP00000377862 | ENSP00000356224 | Protocadherin Fat 4; Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). | Nesprin-1; Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nucleus- centrosome attachment and nuclear migrati [...] | 0.672 |
| FAT4 | VANGL2 | ENSP00000377862 | ENSP00000357040 | Protocadherin Fat 4; Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). | Vang-like protein 2; Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity). | 0.768 |
| FAT4 | ZFHX4 | ENSP00000377862 | ENSP00000498627 | Protocadherin Fat 4; Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). | Zinc finger homeobox protein 4; May play a role in neural and muscle differentiation (By similarity). May be involved in transcriptional regulation. | 0.599 |
| FJX1 | DCHS1 | ENSP00000400223 | ENSP00000299441 | Four-jointed box protein 1; Acts as an inhibitor of dendrite extension and branching. Belongs to the FJX1/FJ family. | Protocadherin-16; Calcium-dependent cell-adhesion protein. Mediates functions in neuroprogenitor cell proliferation and differentiation. In the heart, has a critical role for proper morphogenesis of the mitral valve, acting in the regulation of cell migration involved in valve formation. | 0.667 |
| FJX1 | FAT4 | ENSP00000400223 | ENSP00000377862 | Four-jointed box protein 1; Acts as an inhibitor of dendrite extension and branching. Belongs to the FJX1/FJ family. | Protocadherin Fat 4; Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). | 0.926 |
| FJX1 | LAMC1 | ENSP00000400223 | ENSP00000258341 | Four-jointed box protein 1; Acts as an inhibitor of dendrite extension and branching. Belongs to the FJX1/FJ family. | Laminin subunit gamma-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | 0.423 |
| FJX1 | VANGL2 | ENSP00000400223 | ENSP00000357040 | Four-jointed box protein 1; Acts as an inhibitor of dendrite extension and branching. Belongs to the FJX1/FJ family. | Vang-like protein 2; Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity). | 0.753 |
| LAMC1 | FAT4 | ENSP00000258341 | ENSP00000377862 | Laminin subunit gamma-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | Protocadherin Fat 4; Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). | 0.679 |
| LAMC1 | FJX1 | ENSP00000258341 | ENSP00000400223 | Laminin subunit gamma-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | Four-jointed box protein 1; Acts as an inhibitor of dendrite extension and branching. Belongs to the FJX1/FJ family. | 0.423 |
| MUC16 | FAT4 | ENSP00000381008 | ENSP00000377862 | Mucin-16; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. | Protocadherin Fat 4; Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). | 0.622 |
| MUC16 | PCLO | ENSP00000381008 | ENSP00000334319 | Mucin-16; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. | Protein piccolo; Scaffold protein of the presynaptic cytomatrix at the active zone (CAZ) which is the place in the synapse where neurotransmitter is released (By similarity). After synthesis, participates in the formation of Golgi-derived membranous organelles termed Piccolo-Bassoon transport vesicles (PTVs) that are transported along axons to sites of nascent synaptic contacts (By similarity). At the presynaptic active zone, regulates the spatial organization of synaptic vesicle cluster, the protein complexes that execute membrane fusion and compensatory endocytosis (By similarity). O [...] | 0.725 |