| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANKRD39 | FAHD2B | ENSP00000377170 | ENSP00000410470 | Ankyrin repeat domain 39; Belongs to the ANKRD39 family. | Fumarylacetoacetate hydrolase domain-containing protein 2B; May have hydrolase activity. | 0.584 |
| ANKRD39 | FAM178B | ENSP00000377170 | ENSP00000429896 | Ankyrin repeat domain 39; Belongs to the ANKRD39 family. | Protein FAM178B; Family with sequence similarity 178 member B. | 0.548 |
| ANKRD39 | FER1L5 | ENSP00000377170 | ENSP00000485238 | Ankyrin repeat domain 39; Belongs to the ANKRD39 family. | Fer-1-like protein 5; Plays a role in myoblast fusion; probable mediator of endocytic recycling for membrane trafficking events during myotube formation. | 0.430 |
| DDX39A | FER1L5 | ENSP00000242776 | ENSP00000485238 | ATP-dependent RNA helicase DDX39A; [Isoform 1]: Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus; Belongs to the DEAD box helicase family. DECD subfamily. | Fer-1-like protein 5; Plays a role in myoblast fusion; probable mediator of endocytic recycling for membrane trafficking events during myotube formation. | 0.466 |
| EHD1 | EHD2 | ENSP00000479153 | ENSP00000263277 | EH domain-containing protein 1; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth (By similarity). Plays a role in myoblast fusion (By similarity). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating [...] | EH domain-containing protein 2; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (By similarity). Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane (By similarity). Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane. | 0.727 |
| EHD1 | EHD3 | ENSP00000479153 | ENSP00000327116 | EH domain-containing protein 1; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth (By similarity). Plays a role in myoblast fusion (By similarity). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating [...] | EH domain-containing protein 3; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes tubulation of endocytic membranes. Binding to phosphatidic acid induces its membrane tubulation activity (By similarity). Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology. Involved in the recycling of internalized D1 [...] | 0.999 |
| EHD1 | FER1L5 | ENSP00000479153 | ENSP00000485238 | EH domain-containing protein 1; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth (By similarity). Plays a role in myoblast fusion (By similarity). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating [...] | Fer-1-like protein 5; Plays a role in myoblast fusion; probable mediator of endocytic recycling for membrane trafficking events during myotube formation. | 0.473 |
| EHD2 | EHD1 | ENSP00000263277 | ENSP00000479153 | EH domain-containing protein 2; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (By similarity). Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane (By similarity). Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane. | EH domain-containing protein 1; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth (By similarity). Plays a role in myoblast fusion (By similarity). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating [...] | 0.727 |
| EHD2 | EHD3 | ENSP00000263277 | ENSP00000327116 | EH domain-containing protein 2; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (By similarity). Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane (By similarity). Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane. | EH domain-containing protein 3; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes tubulation of endocytic membranes. Binding to phosphatidic acid induces its membrane tubulation activity (By similarity). Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology. Involved in the recycling of internalized D1 [...] | 0.937 |
| EHD2 | FER1L5 | ENSP00000263277 | ENSP00000485238 | EH domain-containing protein 2; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (By similarity). Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane (By similarity). Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane. | Fer-1-like protein 5; Plays a role in myoblast fusion; probable mediator of endocytic recycling for membrane trafficking events during myotube formation. | 0.515 |
| EHD3 | EHD1 | ENSP00000327116 | ENSP00000479153 | EH domain-containing protein 3; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes tubulation of endocytic membranes. Binding to phosphatidic acid induces its membrane tubulation activity (By similarity). Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology. Involved in the recycling of internalized D1 [...] | EH domain-containing protein 1; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth (By similarity). Plays a role in myoblast fusion (By similarity). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating [...] | 0.999 |
| EHD3 | EHD2 | ENSP00000327116 | ENSP00000263277 | EH domain-containing protein 3; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes tubulation of endocytic membranes. Binding to phosphatidic acid induces its membrane tubulation activity (By similarity). Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology. Involved in the recycling of internalized D1 [...] | EH domain-containing protein 2; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (By similarity). Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane (By similarity). Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane. | 0.937 |
| EHD3 | FER1L5 | ENSP00000327116 | ENSP00000485238 | EH domain-containing protein 3; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes tubulation of endocytic membranes. Binding to phosphatidic acid induces its membrane tubulation activity (By similarity). Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology. Involved in the recycling of internalized D1 [...] | Fer-1-like protein 5; Plays a role in myoblast fusion; probable mediator of endocytic recycling for membrane trafficking events during myotube formation. | 0.438 |
| FAHD2B | ANKRD39 | ENSP00000410470 | ENSP00000377170 | Fumarylacetoacetate hydrolase domain-containing protein 2B; May have hydrolase activity. | Ankyrin repeat domain 39; Belongs to the ANKRD39 family. | 0.584 |
| FAHD2B | FAM178B | ENSP00000410470 | ENSP00000429896 | Fumarylacetoacetate hydrolase domain-containing protein 2B; May have hydrolase activity. | Protein FAM178B; Family with sequence similarity 178 member B. | 0.657 |
| FAHD2B | FER1L5 | ENSP00000410470 | ENSP00000485238 | Fumarylacetoacetate hydrolase domain-containing protein 2B; May have hydrolase activity. | Fer-1-like protein 5; Plays a role in myoblast fusion; probable mediator of endocytic recycling for membrane trafficking events during myotube formation. | 0.451 |
| FAM178B | ANKRD39 | ENSP00000429896 | ENSP00000377170 | Protein FAM178B; Family with sequence similarity 178 member B. | Ankyrin repeat domain 39; Belongs to the ANKRD39 family. | 0.548 |
| FAM178B | FAHD2B | ENSP00000429896 | ENSP00000410470 | Protein FAM178B; Family with sequence similarity 178 member B. | Fumarylacetoacetate hydrolase domain-containing protein 2B; May have hydrolase activity. | 0.657 |
| FAM178B | FER1L5 | ENSP00000429896 | ENSP00000485238 | Protein FAM178B; Family with sequence similarity 178 member B. | Fer-1-like protein 5; Plays a role in myoblast fusion; probable mediator of endocytic recycling for membrane trafficking events during myotube formation. | 0.449 |
| FER1L5 | ANKRD39 | ENSP00000485238 | ENSP00000377170 | Fer-1-like protein 5; Plays a role in myoblast fusion; probable mediator of endocytic recycling for membrane trafficking events during myotube formation. | Ankyrin repeat domain 39; Belongs to the ANKRD39 family. | 0.430 |
