FGFBP2 protein (human) - STRING interaction network

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Score

FGFBP2

Fibroblast growth factor binding protein 2. (223 aa)

Predicted Functional Partners:

GZMH

0.909

GNLY

0.892

ACOT11

0.877

FKBP7

0.874

NKG7

0.798

KLRD1

0.724

S1PR5

0.715

KLRF1

0.702

GZMK

0.663

PRF1

0.658

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACOT11	FGFBP2	ENSP00000360366	ENSP00000259989	Acyl-coenzyme A thioesterase 11; Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.	Fibroblast growth factor binding protein 2.	0.877
ACOT11	FKBP7	ENSP00000360366	ENSP00000413152	Acyl-coenzyme A thioesterase 11; Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.	Peptidyl-prolyl cis-trans isomerase FKBP7; PPIases accelerate the folding of proteins during protein synthesis.	0.585
FGFBP2	ACOT11	ENSP00000259989	ENSP00000360366	Fibroblast growth factor binding protein 2.	Acyl-coenzyme A thioesterase 11; Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.	0.877
FGFBP2	FKBP7	ENSP00000259989	ENSP00000413152	Fibroblast growth factor binding protein 2.	Peptidyl-prolyl cis-trans isomerase FKBP7; PPIases accelerate the folding of proteins during protein synthesis.	0.874
FGFBP2	GNLY	ENSP00000259989	ENSP00000436423	Fibroblast growth factor binding protein 2.	Granulysin; Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.	0.892
FGFBP2	GZMH	ENSP00000259989	ENSP00000216338	Fibroblast growth factor binding protein 2.	Granzyme H; Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication.	0.909
FGFBP2	GZMK	ENSP00000259989	ENSP00000231009	Fibroblast growth factor binding protein 2.	Granzyme K; Belongs to the peptidase S1 family. Granzyme subfamily.	0.663
FGFBP2	KLRD1	ENSP00000259989	ENSP00000338130	Fibroblast growth factor binding protein 2.	Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.	0.724
FGFBP2	KLRF1	ENSP00000259989	ENSP00000483713	Fibroblast growth factor binding protein 2.	Killer cell lectin-like receptor subfamily F member 1; Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.	0.702
FGFBP2	NKG7	ENSP00000259989	ENSP00000221978	Fibroblast growth factor binding protein 2.	Protein NKG7; Natural killer cell granule protein 7; Belongs to the PMP-22/EMP/MP20 family.	0.798
FGFBP2	PRF1	ENSP00000259989	ENSP00000398568	Fibroblast growth factor binding protein 2.	Perforin-1; Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes. Belongs to the complement C6/C7/C8/C9 family.	0.658
FGFBP2	S1PR5	ENSP00000259989	ENSP00000328472	Fibroblast growth factor binding protein 2.	Sphingosine 1-phosphate receptor 5; Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.	0.715
FKBP7	ACOT11	ENSP00000413152	ENSP00000360366	Peptidyl-prolyl cis-trans isomerase FKBP7; PPIases accelerate the folding of proteins during protein synthesis.	Acyl-coenzyme A thioesterase 11; Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.	0.585
FKBP7	FGFBP2	ENSP00000413152	ENSP00000259989	Peptidyl-prolyl cis-trans isomerase FKBP7; PPIases accelerate the folding of proteins during protein synthesis.	Fibroblast growth factor binding protein 2.	0.874
GNLY	FGFBP2	ENSP00000436423	ENSP00000259989	Granulysin; Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.	Fibroblast growth factor binding protein 2.	0.892
GNLY	GZMH	ENSP00000436423	ENSP00000216338	Granulysin; Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.	Granzyme H; Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication.	0.961
GNLY	GZMK	ENSP00000436423	ENSP00000231009	Granulysin; Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.	Granzyme K; Belongs to the peptidase S1 family. Granzyme subfamily.	0.930
GNLY	KLRD1	ENSP00000436423	ENSP00000338130	Granulysin; Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.	Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.	0.941
GNLY	KLRF1	ENSP00000436423	ENSP00000483713	Granulysin; Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.	Killer cell lectin-like receptor subfamily F member 1; Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.	0.808
GNLY	NKG7	ENSP00000436423	ENSP00000221978	Granulysin; Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.	Protein NKG7; Natural killer cell granule protein 7; Belongs to the PMP-22/EMP/MP20 family.	0.979