Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
GASK1AGolgi associated kinase 1A; Belongs to the GASK family. (575 aa)    
Predicted Functional Partners:
MAB21L3
Protein mab-21-like 3; Mab-21 like 3.
   
    0.978
FAM20B
Glycosaminoglycan xylosylkinase; Responsible for the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature GAG chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O- phosphorylation may influence the catalyti [...]
      
 0.670
FJX1
Four-jointed box protein 1; Acts as an inhibitor of dendrite extension and branching. Belongs to the FJX1/FJ family.
      
 0.646
FAM20A
Pseudokinase FAM20A; Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals.
   
  
 0.627
STMND1
Stathmin domain containing 1.
      
 0.606
ZNF662
Zinc finger protein 662; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
   
  
 0.602
NMNAT3
Nicotinamide nucleotide adenylyltransferase 3.
   
    0.589
RNF225
Ring finger protein 225.
      
 0.571
IFNE
Interferon epsilon; Type I interferon required for maintaining basal levels of IFN-regulated genes, including 2'-5'-oligoadenylate synthetase, IRF7 and ISG15, in the female reproductive tract. Directly mediates protection against viral and bacterial genital infections (By similarity).
    
   0.570
KIAA1958
Uncharacterized protein KIAA1958; KIAA1958.
      
 0.544
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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