| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANPEP | GCLC | ENSP00000300060 | ENSP00000497574 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | Glutamate-cysteine ligase catalytic subunit. | 0.937 |
| ANPEP | GCLM | ENSP00000300060 | ENSP00000359258 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | Glutamate-cysteine ligase modifier subunit; Belongs to the aldo/keto reductase family. Glutamate-- cysteine ligase light chain subfamily. | 0.928 |
| ANPEP | GGCT | ENSP00000300060 | ENSP00000275428 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | Gamma-glutamylcyclotransferase; Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis; Belongs to the gamma-glutamylcyclotransferase family. | 0.908 |
| ANPEP | GGT7 | ENSP00000300060 | ENSP00000338964 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | Glutathione hydrolase 7 heavy chain; Cleaves glutathione conjugates; Belongs to the gamma-glutamyltransferase family. | 0.948 |
| ANPEP | GSR | ENSP00000300060 | ENSP00000221130 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | Glutathione reductase, mitochondrial; Maintains high levels of reduced glutathione in the cytosol. | 0.449 |
| ANPEP | GSS | ENSP00000300060 | ENSP00000495750 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | Glutathione synthetase. | 0.916 |
| ANPEP | LAP3 | ENSP00000300060 | ENSP00000226299 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides; Belongs to the peptidase M17 family. | 0.966 |
| GAD1 | GCLC | ENSP00000350928 | ENSP00000497574 | Glutamate decarboxylase 1; Catalyzes the production of GABA. | Glutamate-cysteine ligase catalytic subunit. | 0.815 |
| GAD1 | GCLM | ENSP00000350928 | ENSP00000359258 | Glutamate decarboxylase 1; Catalyzes the production of GABA. | Glutamate-cysteine ligase modifier subunit; Belongs to the aldo/keto reductase family. Glutamate-- cysteine ligase light chain subfamily. | 0.823 |
| GAD1 | GGT7 | ENSP00000350928 | ENSP00000338964 | Glutamate decarboxylase 1; Catalyzes the production of GABA. | Glutathione hydrolase 7 heavy chain; Cleaves glutathione conjugates; Belongs to the gamma-glutamyltransferase family. | 0.922 |
| GAD1 | OPLAH | ENSP00000350928 | ENSP00000480476 | Glutamate decarboxylase 1; Catalyzes the production of GABA. | 5-oxoprolinase; Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate; Belongs to the oxoprolinase family. | 0.811 |
| GCLC | ANPEP | ENSP00000497574 | ENSP00000300060 | Glutamate-cysteine ligase catalytic subunit. | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | 0.937 |
| GCLC | GAD1 | ENSP00000497574 | ENSP00000350928 | Glutamate-cysteine ligase catalytic subunit. | Glutamate decarboxylase 1; Catalyzes the production of GABA. | 0.815 |
| GCLC | GCLM | ENSP00000497574 | ENSP00000359258 | Glutamate-cysteine ligase catalytic subunit. | Glutamate-cysteine ligase modifier subunit; Belongs to the aldo/keto reductase family. Glutamate-- cysteine ligase light chain subfamily. | 0.999 |
| GCLC | GGCT | ENSP00000497574 | ENSP00000275428 | Glutamate-cysteine ligase catalytic subunit. | Gamma-glutamylcyclotransferase; Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis; Belongs to the gamma-glutamylcyclotransferase family. | 0.928 |
| GCLC | GGT7 | ENSP00000497574 | ENSP00000338964 | Glutamate-cysteine ligase catalytic subunit. | Glutathione hydrolase 7 heavy chain; Cleaves glutathione conjugates; Belongs to the gamma-glutamyltransferase family. | 0.929 |
| GCLC | GSR | ENSP00000497574 | ENSP00000221130 | Glutamate-cysteine ligase catalytic subunit. | Glutathione reductase, mitochondrial; Maintains high levels of reduced glutathione in the cytosol. | 0.870 |
| GCLC | GSS | ENSP00000497574 | ENSP00000495750 | Glutamate-cysteine ligase catalytic subunit. | Glutathione synthetase. | 0.997 |
| GCLC | LAP3 | ENSP00000497574 | ENSP00000226299 | Glutamate-cysteine ligase catalytic subunit. | Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides; Belongs to the peptidase M17 family. | 0.925 |
| GCLC | OPLAH | ENSP00000497574 | ENSP00000480476 | Glutamate-cysteine ligase catalytic subunit. | 5-oxoprolinase; Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate; Belongs to the oxoprolinase family. | 0.969 |
