GK5 protein (human) - STRING interaction network

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[Homology]

Score

GK5

Glycerol kinase 5. (529 aa)

Predicted Functional Partners:

GPD2

0.771

CEACAM4

0.547

ICA1L

0.539

GPD1L

0.522

GPD1

0.522

CYP20A1

0.522

DPY19L4

0.508

AQP7

0.501

LOC100509620

0.501

OPA3

0.495

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQP7	GK5	ENSP00000297988	ENSP00000418001	Aquaporin-7; Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH. The channel is also permeable to urea. Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney (By similarity). Belongs to the MIP/aqua [...]	Glycerol kinase 5.	0.501
AQP7	GPD1	ENSP00000297988	ENSP00000301149	Aquaporin-7; Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH. The channel is also permeable to urea. Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney (By similarity). Belongs to the MIP/aqua [...]	Glycerol-3-phosphate dehydrogenase 1; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.	0.518
AQP7	GPD2	ENSP00000297988	ENSP00000308610	Aquaporin-7; Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH. The channel is also permeable to urea. Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney (By similarity). Belongs to the MIP/aqua [...]	Glycerol-3-phosphate dehydrogenase, mitochondrial; Glycerol-3-phosphate dehydrogenase 2; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.	0.469
AQP7	LOC100509620	ENSP00000297988	ENSP00000456868	Aquaporin-7; Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH. The channel is also permeable to urea. Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney (By similarity). Belongs to the MIP/aqua [...]	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.902
CEACAM4	GK5	ENSP00000221954	ENSP00000418001	Carcinoembryonic antigen-related cell adhesion molecule 4; Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles.	Glycerol kinase 5.	0.547
CYP20A1	GK5	ENSP00000348380	ENSP00000418001	Cytochrome P450 family 20 subfamily A member 1.	Glycerol kinase 5.	0.522
CYP20A1	ICA1L	ENSP00000348380	ENSP00000478645	Cytochrome P450 family 20 subfamily A member 1.	Islet cell autoantigen 1 like.	0.568
CYP20A1	OPA3	ENSP00000348380	ENSP00000319817	Cytochrome P450 family 20 subfamily A member 1.	Outer mitochondrial membrane lipid metabolism regulator OPA3.	0.495
DPY19L4	GK5	ENSP00000389630	ENSP00000418001	Probable C-mannosyltransferase DPY19L4; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.	Glycerol kinase 5.	0.508
GK5	AQP7	ENSP00000418001	ENSP00000297988	Glycerol kinase 5.	Aquaporin-7; Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH. The channel is also permeable to urea. Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney (By similarity). Belongs to the MIP/aqua [...]	0.501
GK5	CEACAM4	ENSP00000418001	ENSP00000221954	Glycerol kinase 5.	Carcinoembryonic antigen-related cell adhesion molecule 4; Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles.	0.547
GK5	CYP20A1	ENSP00000418001	ENSP00000348380	Glycerol kinase 5.	Cytochrome P450 family 20 subfamily A member 1.	0.522
GK5	DPY19L4	ENSP00000418001	ENSP00000389630	Glycerol kinase 5.	Probable C-mannosyltransferase DPY19L4; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.	0.508
GK5	GPD1	ENSP00000418001	ENSP00000301149	Glycerol kinase 5.	Glycerol-3-phosphate dehydrogenase 1; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.	0.522
GK5	GPD1L	ENSP00000418001	ENSP00000282541	Glycerol kinase 5.	Glycerol-3-phosphate dehydrogenase 1-like protein; Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3- phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.	0.522
GK5	GPD2	ENSP00000418001	ENSP00000308610	Glycerol kinase 5.	Glycerol-3-phosphate dehydrogenase, mitochondrial; Glycerol-3-phosphate dehydrogenase 2; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.	0.771
GK5	ICA1L	ENSP00000418001	ENSP00000478645	Glycerol kinase 5.	Islet cell autoantigen 1 like.	0.539
GK5	LOC100509620	ENSP00000418001	ENSP00000456868	Glycerol kinase 5.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.501
GK5	OPA3	ENSP00000418001	ENSP00000319817	Glycerol kinase 5.	Outer mitochondrial membrane lipid metabolism regulator OPA3.	0.495
GPD1	AQP7	ENSP00000301149	ENSP00000297988	Glycerol-3-phosphate dehydrogenase 1; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.	Aquaporin-7; Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH. The channel is also permeable to urea. Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney (By similarity). Belongs to the MIP/aqua [...]	0.518