GMCL1 protein (human) - STRING interaction network

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GMCL1

Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity). (515 aa)

Predicted Functional Partners:

XAGE2

0.965

FAM167A

0.843

GAGE10

0.839

XAGE3

0.833

GAGE12G

0.811

PBXIP1

0.794

GAGE2E

0.626

GAGE2A

0.623

PAX4

0.608

SPATA4

0.596

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM167A	GMCL1	ENSP00000284486	ENSP00000282570	Protein FAM167A; Family with sequence similarity 167 member A; Belongs to the FAM167 (SEC) family.	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	0.843
GAGE10	GMCL1	ENSP00000385415	ENSP00000282570	G antigen 10; Belongs to the GAGE family.	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	0.839
GAGE12G	GAGE2A	ENSP00000416249	ENSP00000355421	G antigen 12G.	G antigen 2A.	0.910
GAGE12G	GAGE2E	ENSP00000416249	ENSP00000478568	G antigen 12G.	G antigen 2E.	0.975
GAGE12G	GMCL1	ENSP00000416249	ENSP00000282570	G antigen 12G.	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	0.811
GAGE2A	GAGE12G	ENSP00000355421	ENSP00000416249	G antigen 2A.	G antigen 12G.	0.910
GAGE2A	GAGE2E	ENSP00000355421	ENSP00000478568	G antigen 2A.	G antigen 2E.	0.532
GAGE2A	GMCL1	ENSP00000355421	ENSP00000282570	G antigen 2A.	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	0.623
GAGE2E	GAGE12G	ENSP00000478568	ENSP00000416249	G antigen 2E.	G antigen 12G.	0.975
GAGE2E	GAGE2A	ENSP00000478568	ENSP00000355421	G antigen 2E.	G antigen 2A.	0.532
GAGE2E	GMCL1	ENSP00000478568	ENSP00000282570	G antigen 2E.	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	0.626
GMCL1	FAM167A	ENSP00000282570	ENSP00000284486	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	Protein FAM167A; Family with sequence similarity 167 member A; Belongs to the FAM167 (SEC) family.	0.843
GMCL1	GAGE10	ENSP00000282570	ENSP00000385415	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	G antigen 10; Belongs to the GAGE family.	0.839
GMCL1	GAGE12G	ENSP00000282570	ENSP00000416249	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	G antigen 12G.	0.811
GMCL1	GAGE2A	ENSP00000282570	ENSP00000355421	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	G antigen 2A.	0.623
GMCL1	GAGE2E	ENSP00000282570	ENSP00000478568	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	G antigen 2E.	0.626
GMCL1	PAX4	ENSP00000282570	ENSP00000368014	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	Paired box protein Pax-4; Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.	0.608
GMCL1	PBXIP1	ENSP00000282570	ENSP00000357448	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	Pre-B-cell leukemia transcription factor-interacting protein 1; Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor- alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.	0.794
GMCL1	SPATA4	ENSP00000282570	ENSP00000280191	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	Spermatogenesis-associated protein 4; May play a role in apoptosis regulation.	0.596
GMCL1	XAGE2	ENSP00000282570	ENSP00000286049	Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity).	X antigen family member 2.	0.965

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