| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARL1 | GCC1 | ENSP00000261636 | ENSP00000318821 | ADP-ribosylation factor-like protein 1; GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure. | 0.870 |
| ARL1 | GCC2 | ENSP00000261636 | ENSP00000307939 | ADP-ribosylation factor-like protein 1; GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. | GRIP and coiled-coil domain-containing protein 2; Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi- associated microtubules through recruitment of CLASP1 and CLASP2. | 0.941 |
| ARL1 | GOLGA1 | ENSP00000261636 | ENSP00000362656 | ADP-ribosylation factor-like protein 1; GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. | Golgin subfamily A member 1; Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking. | 0.814 |
| ARL1 | GOLGA4 | ENSP00000261636 | ENSP00000349305 | ADP-ribosylation factor-like protein 1; GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. | Golgin subfamily A member 4; Involved in vesicular trafficking at the Golgi apparatus level. May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1. Involved in endosome-to-Golgi trafficking. | 0.992 |
| ARL1 | GRIP1 | ENSP00000261636 | ENSP00000381098 | ADP-ribosylation factor-like protein 1; GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. | Glutamate receptor-interacting protein 1; May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons. Through complex formation with NSG1, GRIA2 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity). | 0.869 |
| ARL1 | TGOLN2 | ENSP00000261636 | ENSP00000386443 | ADP-ribosylation factor-like protein 1; GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. | Trans-Golgi network integral membrane protein 2; May be involved in regulating membrane traffic to and from trans-Golgi network. | 0.628 |
| EXOC1 | GOLGA4 | ENSP00000370695 | ENSP00000349305 | Exocyst complex component 1; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. | Golgin subfamily A member 4; Involved in vesicular trafficking at the Golgi apparatus level. May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1. Involved in endosome-to-Golgi trafficking. | 0.810 |
| GCC1 | ARL1 | ENSP00000318821 | ENSP00000261636 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure. | ADP-ribosylation factor-like protein 1; GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. | 0.870 |
| GCC1 | GCC2 | ENSP00000318821 | ENSP00000307939 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure. | GRIP and coiled-coil domain-containing protein 2; Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi- associated microtubules through recruitment of CLASP1 and CLASP2. | 0.822 |
| GCC1 | GOLGA1 | ENSP00000318821 | ENSP00000362656 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure. | Golgin subfamily A member 1; Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking. | 0.912 |
| GCC1 | GOLGA4 | ENSP00000318821 | ENSP00000349305 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure. | Golgin subfamily A member 4; Involved in vesicular trafficking at the Golgi apparatus level. May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1. Involved in endosome-to-Golgi trafficking. | 0.963 |
| GCC1 | GOLGB1 | ENSP00000318821 | ENSP00000377275 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure. | Golgin subfamily B member 1; May participate in forming intercisternal cross-bridges of the Golgi complex. | 0.526 |
| GCC1 | GRIP1 | ENSP00000318821 | ENSP00000381098 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure. | Glutamate receptor-interacting protein 1; May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons. Through complex formation with NSG1, GRIA2 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity). | 0.905 |
| GCC1 | TGOLN2 | ENSP00000318821 | ENSP00000386443 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure. | Trans-Golgi network integral membrane protein 2; May be involved in regulating membrane traffic to and from trans-Golgi network. | 0.923 |
| GCC1 | TRIP11 | ENSP00000318821 | ENSP00000267622 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure. | Thyroid receptor-interacting protein 11; Is a membrane tether required for vesicle tethering to Golgi. Has an essential role in the maintenance of Golgi structure and function. It is required for efficient anterograde and retrograde trafficking in the early secretory pathway, functioning at both the ER-to-Golgi intermediate compartment (ERGIC) and Golgi complex. Binds the ligand binding domain of the thyroid receptor (THRB) in the presence of triiodothyronine and enhances THRB-modulated transcription. | 0.584 |
| GCC2 | ARL1 | ENSP00000307939 | ENSP00000261636 | GRIP and coiled-coil domain-containing protein 2; Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi- associated microtubules through recruitment of CLASP1 and CLASP2. | ADP-ribosylation factor-like protein 1; GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. | 0.941 |
| GCC2 | GCC1 | ENSP00000307939 | ENSP00000318821 | GRIP and coiled-coil domain-containing protein 2; Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi- associated microtubules through recruitment of CLASP1 and CLASP2. | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure. | 0.822 |
| GCC2 | GOLGA1 | ENSP00000307939 | ENSP00000362656 | GRIP and coiled-coil domain-containing protein 2; Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi- associated microtubules through recruitment of CLASP1 and CLASP2. | Golgin subfamily A member 1; Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking. | 0.858 |
| GCC2 | GOLGA4 | ENSP00000307939 | ENSP00000349305 | GRIP and coiled-coil domain-containing protein 2; Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi- associated microtubules through recruitment of CLASP1 and CLASP2. | Golgin subfamily A member 4; Involved in vesicular trafficking at the Golgi apparatus level. May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1. Involved in endosome-to-Golgi trafficking. | 0.953 |
| GCC2 | GOLGB1 | ENSP00000307939 | ENSP00000377275 | GRIP and coiled-coil domain-containing protein 2; Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi- associated microtubules through recruitment of CLASP1 and CLASP2. | Golgin subfamily B member 1; May participate in forming intercisternal cross-bridges of the Golgi complex. | 0.849 |
