GPRIN1 protein (human) - STRING interaction network

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Score

GPRIN1

G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth. (1008 aa)

Predicted Functional Partners:

MECP2

0.894

GNAZ

0.770

GNAO1

0.632

SDF4

0.612

TUBA1B

0.562

TMEM185A

0.557

VTN

0.548

STAMBPL1

0.547

RBFOX1

0.542

CDHR2

0.541

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDHR2	GPRIN1	ENSP00000424565	ENSP00000305839	Cadherin-related family member 2; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells.	G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.	0.541
GNAO1	GNAZ	ENSP00000262494	ENSP00000478892	Guanine nucleotide-binding protein G(o) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14; Belongs to the G-alpha family. G(i/o/t/z) subfamily.	Guanine nucleotide-binding protein G(z) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	0.940
GNAO1	GPRIN1	ENSP00000262494	ENSP00000305839	Guanine nucleotide-binding protein G(o) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14; Belongs to the G-alpha family. G(i/o/t/z) subfamily.	G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.	0.632
GNAZ	GNAO1	ENSP00000478892	ENSP00000262494	Guanine nucleotide-binding protein G(z) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	Guanine nucleotide-binding protein G(o) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14; Belongs to the G-alpha family. G(i/o/t/z) subfamily.	0.940
GNAZ	GPRIN1	ENSP00000478892	ENSP00000305839	Guanine nucleotide-binding protein G(z) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.	0.770
GNAZ	TMEM185A	ENSP00000478892	ENSP00000471932	Guanine nucleotide-binding protein G(z) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	Transmembrane protein 185A; Belongs to the TMEM185 family.	0.524
GPRIN1	CDHR2	ENSP00000305839	ENSP00000424565	G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.	Cadherin-related family member 2; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells.	0.541
GPRIN1	GNAO1	ENSP00000305839	ENSP00000262494	G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.	Guanine nucleotide-binding protein G(o) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14; Belongs to the G-alpha family. G(i/o/t/z) subfamily.	0.632
GPRIN1	GNAZ	ENSP00000305839	ENSP00000478892	G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.	Guanine nucleotide-binding protein G(z) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	0.770
GPRIN1	MECP2	ENSP00000305839	ENSP00000395535	G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC).	0.894
GPRIN1	RBFOX1	ENSP00000305839	ENSP00000391269	G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.	RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.	0.542
GPRIN1	SDF4	ENSP00000305839	ENSP00000499387	G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.	45 kDa calcium-binding protein; May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment; Belongs to the CREC family.	0.612
GPRIN1	STAMBPL1	ENSP00000305839	ENSP00000360992	G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.	AMSH-like protease; Zinc metalloprotease that specifically cleaves 'Lys-63'- linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains; Belongs to the peptidase M67C family.	0.547
GPRIN1	TMEM185A	ENSP00000305839	ENSP00000471932	G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.	Transmembrane protein 185A; Belongs to the TMEM185 family.	0.557
GPRIN1	TUBA1B	ENSP00000305839	ENSP00000336799	G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.	Detyrosinated tubulin alpha-1B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.562
GPRIN1	VTN	ENSP00000305839	ENSP00000226218	G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.	Vitronectin V10 subunit; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.	0.548
MECP2	GPRIN1	ENSP00000395535	ENSP00000305839	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC).	G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.	0.894
MECP2	RBFOX1	ENSP00000395535	ENSP00000391269	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC).	RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.	0.922
RBFOX1	GPRIN1	ENSP00000391269	ENSP00000305839	RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.	G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.	0.542
RBFOX1	MECP2	ENSP00000391269	ENSP00000395535	RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC).	0.922