| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADPRHL1 | DCUN1D2 | ENSP00000364567 | ENSP00000417706 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1. | DCN1-like protein 2; Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. | 0.642 |
| ADPRHL1 | GRTP1 | ENSP00000364567 | ENSP00000364579 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1. | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | 0.706 |
| ADPRHL1 | TMCO3 | ENSP00000364567 | ENSP00000389399 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1. | Transmembrane and coiled-coil domain-containing protein 3; Probable Na(+)/H(+) antiporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.543 |
| AIF1L | GRTP1 | ENSP00000361383 | ENSP00000364579 | Allograft inflammatory factor 1-like; Actin-binding protein that promotes actin bundling. May neither bind calcium nor depend on calcium for function. | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | 0.521 |
| ATP4B | GRTP1 | ENSP00000334216 | ENSP00000364579 | Potassium-transporting ATPase subunit beta; Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity. | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | 0.541 |
| ATP4B | PCID2 | ENSP00000334216 | ENSP00000479494 | Potassium-transporting ATPase subunit beta; Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity. | PCI domain-containing protein 2; Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (Probable). Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells. | 0.468 |
| ATP4B | TMCO3 | ENSP00000334216 | ENSP00000389399 | Potassium-transporting ATPase subunit beta; Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity. | Transmembrane and coiled-coil domain-containing protein 3; Probable Na(+)/H(+) antiporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.551 |
| DCUN1D2 | ADPRHL1 | ENSP00000417706 | ENSP00000364567 | DCN1-like protein 2; Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1. | 0.642 |
| DCUN1D2 | GRTP1 | ENSP00000417706 | ENSP00000364579 | DCN1-like protein 2; Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | 0.614 |
| DCUN1D2 | PCID2 | ENSP00000417706 | ENSP00000479494 | DCN1-like protein 2; Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. | PCI domain-containing protein 2; Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (Probable). Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells. | 0.416 |
| DCUN1D2 | TFDP1 | ENSP00000417706 | ENSP00000364519 | DCN1-like protein 2; Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. | Transcription factor Dp-1; Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters ; Belongs to the E2F/DP family. | 0.404 |
| DCUN1D2 | TMCO3 | ENSP00000417706 | ENSP00000389399 | DCN1-like protein 2; Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. | Transmembrane and coiled-coil domain-containing protein 3; Probable Na(+)/H(+) antiporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.567 |
| GJB7 | GRTP1 | ENSP00000435355 | ENSP00000364579 | Gap junction beta-7 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell; Belongs to the connexin family. Beta-type (group I) subfamily. | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | 0.602 |
| GRTP1 | ADPRHL1 | ENSP00000364579 | ENSP00000364567 | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1. | 0.706 |
| GRTP1 | AIF1L | ENSP00000364579 | ENSP00000361383 | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | Allograft inflammatory factor 1-like; Actin-binding protein that promotes actin bundling. May neither bind calcium nor depend on calcium for function. | 0.521 |
| GRTP1 | ATP4B | ENSP00000364579 | ENSP00000334216 | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | Potassium-transporting ATPase subunit beta; Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity. | 0.541 |
| GRTP1 | DCUN1D2 | ENSP00000364579 | ENSP00000417706 | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | DCN1-like protein 2; Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. | 0.614 |
| GRTP1 | GJB7 | ENSP00000364579 | ENSP00000435355 | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | Gap junction beta-7 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell; Belongs to the connexin family. Beta-type (group I) subfamily. | 0.602 |
| GRTP1 | KIF14 | ENSP00000364579 | ENSP00000356319 | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | Kinesin-like protein KIF14; Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis. During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively. Regulates cell growth through regulation of cell cycle progression and cytokinesis. During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic [...] | 0.495 |
| GRTP1 | PCID2 | ENSP00000364579 | ENSP00000479494 | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | PCI domain-containing protein 2; Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (Probable). Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells. | 0.636 |