H3C11 protein (human) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

H3C11

H3 clustered histone 11. (136 aa)

Predicted Functional Partners:

H3C7

0.999

H4C13

0.982

H4C2

0.981

H4C5

0.970

H4C4

0.969

H4C9

0.968

H4C11

0.966

H2AC6

0.966

H4C1

0.966

H4-16

0.965

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2AC6	H3C11	ENSP00000367022	ENSP00000483283	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H3 clustered histone 11.	0.966
H2AC6	H3C7	ENSP00000367022	ENSP00000484095	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H3 clustered histone 7.	0.969
H2AC6	H4-16	ENSP00000367022	ENSP00000443017	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 histone 16.	0.966
H2AC6	H4C1	ENSP00000367022	ENSP00000479106	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 1.	0.967
H2AC6	H4C11	ENSP00000367022	ENSP00000347168	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 11.	0.967
H2AC6	H4C13	ENSP00000367022	ENSP00000480960	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 13.	0.966
H2AC6	H4C2	ENSP00000367022	ENSP00000366974	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 2.	0.967
H2AC6	H4C4	ENSP00000367022	ENSP00000479461	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 4.	0.967
H2AC6	H4C5	ENSP00000367022	ENSP00000484789	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 5.	0.992
H2AC6	H4C9	ENSP00000367022	ENSP00000481486	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 9.	0.968
H3C11	H2AC6	ENSP00000483283	ENSP00000367022	H3 clustered histone 11.	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.966
H3C11	H3C7	ENSP00000483283	ENSP00000484095	H3 clustered histone 11.	H3 clustered histone 7.	0.999
H3C11	H4-16	ENSP00000483283	ENSP00000443017	H3 clustered histone 11.	H4 histone 16.	0.965
H3C11	H4C1	ENSP00000483283	ENSP00000479106	H3 clustered histone 11.	H4 clustered histone 1.	0.966
H3C11	H4C11	ENSP00000483283	ENSP00000347168	H3 clustered histone 11.	H4 clustered histone 11.	0.966
H3C11	H4C13	ENSP00000483283	ENSP00000480960	H3 clustered histone 11.	H4 clustered histone 13.	0.982
H3C11	H4C2	ENSP00000483283	ENSP00000366974	H3 clustered histone 11.	H4 clustered histone 2.	0.981
H3C11	H4C4	ENSP00000483283	ENSP00000479461	H3 clustered histone 11.	H4 clustered histone 4.	0.969
H3C11	H4C5	ENSP00000483283	ENSP00000484789	H3 clustered histone 11.	H4 clustered histone 5.	0.970
H3C11	H4C9	ENSP00000483283	ENSP00000481486	H3 clustered histone 11.	H4 clustered histone 9.	0.968