H3C7 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

H3C7

H3 clustered histone 7. (136 aa)

Predicted Functional Partners:

H3C11

0.999

H4C14

0.996

H4C5

0.986

H4C8

0.979

H4C4

0.975

H2AC17

0.974

H4C2

0.974

H2AC13

0.973

H4C13

0.971

H4C11

0.970

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2AC13	H2AC17	ENSP00000351589	ENSP00000352627	Histone H2A type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H2A clustered histone 17.	0.973
H2AC13	H3C11	ENSP00000351589	ENSP00000483283	Histone H2A type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H3 clustered histone 11.	0.958
H2AC13	H3C7	ENSP00000351589	ENSP00000484095	Histone H2A type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H3 clustered histone 7.	0.973
H2AC13	H4C11	ENSP00000351589	ENSP00000347168	Histone H2A type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 11.	0.960
H2AC13	H4C13	ENSP00000351589	ENSP00000480960	Histone H2A type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 13.	0.952
H2AC13	H4C14	ENSP00000351589	ENSP00000462667	Histone H2A type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 14.	0.952
H2AC13	H4C2	ENSP00000351589	ENSP00000366974	Histone H2A type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 2.	0.962
H2AC13	H4C4	ENSP00000351589	ENSP00000479461	Histone H2A type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 4.	0.962
H2AC13	H4C5	ENSP00000351589	ENSP00000484789	Histone H2A type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 5.	0.970
H2AC13	H4C8	ENSP00000351589	ENSP00000489236	Histone H2A type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 8.	0.953
H2AC17	H2AC13	ENSP00000352627	ENSP00000351589	H2A clustered histone 17.	Histone H2A type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.973
H2AC17	H3C11	ENSP00000352627	ENSP00000483283	H2A clustered histone 17.	H3 clustered histone 11.	0.947
H2AC17	H3C7	ENSP00000352627	ENSP00000484095	H2A clustered histone 17.	H3 clustered histone 7.	0.974
H2AC17	H4C11	ENSP00000352627	ENSP00000347168	H2A clustered histone 17.	H4 clustered histone 11.	0.957
H2AC17	H4C13	ENSP00000352627	ENSP00000480960	H2A clustered histone 17.	H4 clustered histone 13.	0.942
H2AC17	H4C14	ENSP00000352627	ENSP00000462667	H2A clustered histone 17.	H4 clustered histone 14.	0.966
H2AC17	H4C2	ENSP00000352627	ENSP00000366974	H2A clustered histone 17.	H4 clustered histone 2.	0.952
H2AC17	H4C4	ENSP00000352627	ENSP00000479461	H2A clustered histone 17.	H4 clustered histone 4.	0.957
H2AC17	H4C5	ENSP00000352627	ENSP00000484789	H2A clustered histone 17.	H4 clustered histone 5.	0.982
H2AC17	H4C8	ENSP00000352627	ENSP00000489236	H2A clustered histone 17.	H4 clustered histone 8.	0.969