IQCJ protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

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[Homology]

Score

IQCJ

IQ motif containing J. (159 aa)

Predicted Functional Partners:

SCHIP1

0.984

NRGN

0.721

GAP43

0.600

NF2

0.553

PRR23A

0.493

HEATR5A

0.440

C11orf53

0.423

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C11orf53	IQCJ	ENSP00000489630	ENSP00000402153	Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53.	IQ motif containing J.	0.423
GAP43	IQCJ	ENSP00000377372	ENSP00000402153	Neuromodulin; This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.	IQ motif containing J.	0.600
GAP43	NRGN	ENSP00000377372	ENSP00000284292	Neuromodulin; This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.	NEUG(55-78); Acts as a 'third messenger' substrate of protein kinase C- mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity). Belongs to the neurogranin family.	0.841
GAP43	SCHIP1	ENSP00000377372	ENSP00000404860	Neuromodulin; This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.	Schwannomin interacting protein 1.	0.576
HEATR5A	IQCJ	ENSP00000437968	ENSP00000402153	HEAT repeat containing 5A.	IQ motif containing J.	0.440
IQCJ	C11orf53	ENSP00000402153	ENSP00000489630	IQ motif containing J.	Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53.	0.423
IQCJ	GAP43	ENSP00000402153	ENSP00000377372	IQ motif containing J.	Neuromodulin; This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.	0.600
IQCJ	HEATR5A	ENSP00000402153	ENSP00000437968	IQ motif containing J.	HEAT repeat containing 5A.	0.440
IQCJ	NF2	ENSP00000402153	ENSP00000344666	IQ motif containing J.	Merlin; Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF [...]	0.553
IQCJ	NRGN	ENSP00000402153	ENSP00000284292	IQ motif containing J.	NEUG(55-78); Acts as a 'third messenger' substrate of protein kinase C- mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity). Belongs to the neurogranin family.	0.721
IQCJ	PRR23A	ENSP00000402153	ENSP00000372649	IQ motif containing J.	Proline-rich protein 23A; Proline rich 23A; Belongs to the PRR23 family.	0.493
IQCJ	SCHIP1	ENSP00000402153	ENSP00000404860	IQ motif containing J.	Schwannomin interacting protein 1.	0.984
NF2	IQCJ	ENSP00000344666	ENSP00000402153	Merlin; Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF [...]	IQ motif containing J.	0.553
NF2	SCHIP1	ENSP00000344666	ENSP00000404860	Merlin; Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF [...]	Schwannomin interacting protein 1.	0.867
NRGN	GAP43	ENSP00000284292	ENSP00000377372	NEUG(55-78); Acts as a 'third messenger' substrate of protein kinase C- mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity). Belongs to the neurogranin family.	Neuromodulin; This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.	0.841
NRGN	IQCJ	ENSP00000284292	ENSP00000402153	NEUG(55-78); Acts as a 'third messenger' substrate of protein kinase C- mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity). Belongs to the neurogranin family.	IQ motif containing J.	0.721
NRGN	SCHIP1	ENSP00000284292	ENSP00000404860	NEUG(55-78); Acts as a 'third messenger' substrate of protein kinase C- mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity). Belongs to the neurogranin family.	Schwannomin interacting protein 1.	0.669
PRR23A	IQCJ	ENSP00000372649	ENSP00000402153	Proline-rich protein 23A; Proline rich 23A; Belongs to the PRR23 family.	IQ motif containing J.	0.493
SCHIP1	GAP43	ENSP00000404860	ENSP00000377372	Schwannomin interacting protein 1.	Neuromodulin; This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.	0.576
SCHIP1	IQCJ	ENSP00000404860	ENSP00000402153	Schwannomin interacting protein 1.	IQ motif containing J.	0.984