Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KRT31Keratin, type I cuticular Ha1; Keratin 31. (416 aa)    
Predicted Functional Partners:
KRT33B
Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family.
  
0.981
KRT32
Keratin, type I cuticular Ha2; Keratin 32; Belongs to the intermediate filament family.
  
 
0.968
KRT38
Keratin, type I cuticular Ha8; Keratin 38; Belongs to the intermediate filament family.
  
 
0.966
KRT36
Keratin, type I cuticular Ha6; Keratin 36; Belongs to the intermediate filament family.
  
 
0.966
KRT37
Keratin, type I cuticular Ha7; Keratin 37.
  
 
0.965
KRT35
Keratin, type I cuticular Ha5; Keratin 35; Belongs to the intermediate filament family.
  
 
0.965
KRT6A
Keratin, type II cytoskeletal 6A; Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. Belongs to the intermediate filament family.
  
 
0.953
KRT33A
Keratin, type I cuticular Ha3-I; Keratin 33A; Belongs to the intermediate filament family.
  
0.941
KRT24
Keratin, type I cytoskeletal 24; Keratin 24; Belongs to the intermediate filament family.
  
 
0.901
KRT76
Keratin, type II cytoskeletal 2 oral; Probably contributes to terminal cornification. Belongs to the intermediate filament family.
   
 
0.860
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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