LCE1E protein (human) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

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[Homology]

Score

LCE1E

Late cornified envelope protein 1E; Precursors of the cornified envelope of the stratum corneum. (118 aa)

Predicted Functional Partners:

LCE1D

0.999

LCE1A

0.994

LCE1F

0.993

LCE1C

0.992

LCE5A

0.990

LCE1B

0.981

LCE3B

0.933

LCE2B

0.903

LCE2C

0.889

LCE4A

0.867

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LCE1A	LCE1B	ENSP00000334869	ENSP00000353203	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	0.977
LCE1A	LCE1C	ENSP00000334869	ENSP00000475270	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1C; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.995
LCE1A	LCE1D	ENSP00000334869	ENSP00000316737	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1D; Precursors of the cornified envelope of the stratum corneum.	0.992
LCE1A	LCE1E	ENSP00000334869	ENSP00000357759	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1E; Precursors of the cornified envelope of the stratum corneum.	0.994
LCE1A	LCE1F	ENSP00000334869	ENSP00000334187	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1F; Precursors of the cornified envelope of the stratum corneum.	0.994
LCE1A	LCE2B	ENSP00000334869	ENSP00000357769	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum.	0.997
LCE1A	LCE2C	ENSP00000334869	ENSP00000357772	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum.	0.987
LCE1A	LCE3B	ENSP00000334869	ENSP00000335358	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3B; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens.	0.930
LCE1A	LCE4A	ENSP00000334869	ENSP00000357766	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 4A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.966
LCE1A	LCE5A	ENSP00000334869	ENSP00000333952	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 5A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.997
LCE1B	LCE1A	ENSP00000353203	ENSP00000334869	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	0.977
LCE1B	LCE1C	ENSP00000353203	ENSP00000475270	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1C; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.980
LCE1B	LCE1D	ENSP00000353203	ENSP00000316737	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1D; Precursors of the cornified envelope of the stratum corneum.	0.932
LCE1B	LCE1E	ENSP00000353203	ENSP00000357759	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1E; Precursors of the cornified envelope of the stratum corneum.	0.981
LCE1B	LCE1F	ENSP00000353203	ENSP00000334187	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1F; Precursors of the cornified envelope of the stratum corneum.	0.903
LCE1B	LCE2B	ENSP00000353203	ENSP00000357769	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum.	0.995
LCE1B	LCE2C	ENSP00000353203	ENSP00000357772	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum.	0.993
LCE1B	LCE3B	ENSP00000353203	ENSP00000335358	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3B; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens.	0.852
LCE1B	LCE4A	ENSP00000353203	ENSP00000357766	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 4A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.987
LCE1B	LCE5A	ENSP00000353203	ENSP00000333952	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 5A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.906