LCE2B protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

LCE2B

Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum. (110 aa)

Predicted Functional Partners:

LCE1A

0.997

LCE2C

0.997

LCE1B

0.995

LCE6A

0.995

LCE2D

0.994

LCE3D

0.993

LCE4A

0.991

LCE3A

0.987

LCE2A

0.985

LCE1F

0.976

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LCE1A	LCE1B	ENSP00000334869	ENSP00000353203	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	0.977
LCE1A	LCE1F	ENSP00000334869	ENSP00000334187	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1F; Precursors of the cornified envelope of the stratum corneum.	0.994
LCE1A	LCE2A	ENSP00000334869	ENSP00000357768	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2A; Precursors of the cornified envelope of the stratum corneum.	0.920
LCE1A	LCE2B	ENSP00000334869	ENSP00000357769	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum.	0.997
LCE1A	LCE2C	ENSP00000334869	ENSP00000357772	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum.	0.987
LCE1A	LCE2D	ENSP00000334869	ENSP00000357773	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum.	0.996
LCE1A	LCE3A	ENSP00000334869	ENSP00000335006	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3A; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens ; Belongs to the LCE family.	0.750
LCE1A	LCE3D	ENSP00000334869	ENSP00000357776	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3D; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.768
LCE1A	LCE4A	ENSP00000334869	ENSP00000357766	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 4A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.966
LCE1A	LCE6A	ENSP00000334869	ENSP00000411070	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 6A; Precursors of the cornified envelope of the stratum corneum. Belongs to the LCE family.	0.971
LCE1B	LCE1A	ENSP00000353203	ENSP00000334869	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	0.977
LCE1B	LCE1F	ENSP00000353203	ENSP00000334187	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1F; Precursors of the cornified envelope of the stratum corneum.	0.903
LCE1B	LCE2A	ENSP00000353203	ENSP00000357768	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2A; Precursors of the cornified envelope of the stratum corneum.	0.993
LCE1B	LCE2B	ENSP00000353203	ENSP00000357769	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum.	0.995
LCE1B	LCE2C	ENSP00000353203	ENSP00000357772	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum.	0.993
LCE1B	LCE2D	ENSP00000353203	ENSP00000357773	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum.	0.994
LCE1B	LCE3A	ENSP00000353203	ENSP00000335006	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3A; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens ; Belongs to the LCE family.	0.977
LCE1B	LCE3D	ENSP00000353203	ENSP00000357776	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3D; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.983
LCE1B	LCE4A	ENSP00000353203	ENSP00000357766	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 4A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.987
LCE1B	LCE6A	ENSP00000353203	ENSP00000411070	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 6A; Precursors of the cornified envelope of the stratum corneum. Belongs to the LCE family.	0.802