LCE4A protein (human) - STRING interaction network

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LCE4A

Late cornified envelope protein 4A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family. (99 aa)

Predicted Functional Partners:

LCE5A

0.994

LCE2B

0.991

LCE2C

0.991

LCE1B

0.987

LCE2A

0.986

LCE2D

0.980

LCE3D

0.978

LCE3A

0.976

LCE1A

0.966

KRTAP9-2

0.933

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KRTAP9-2	LCE1B	ENSP00000366950	ENSP00000353203	Keratin-associated protein 9-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	0.951
KRTAP9-2	LCE2A	ENSP00000366950	ENSP00000357768	Keratin-associated protein 9-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.	Late cornified envelope protein 2A; Precursors of the cornified envelope of the stratum corneum.	0.600
KRTAP9-2	LCE4A	ENSP00000366950	ENSP00000357766	Keratin-associated protein 9-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.	Late cornified envelope protein 4A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.933
LCE1A	LCE1B	ENSP00000334869	ENSP00000353203	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	0.977
LCE1A	LCE2A	ENSP00000334869	ENSP00000357768	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2A; Precursors of the cornified envelope of the stratum corneum.	0.920
LCE1A	LCE2B	ENSP00000334869	ENSP00000357769	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum.	0.997
LCE1A	LCE2C	ENSP00000334869	ENSP00000357772	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum.	0.987
LCE1A	LCE2D	ENSP00000334869	ENSP00000357773	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum.	0.996
LCE1A	LCE3A	ENSP00000334869	ENSP00000335006	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3A; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens ; Belongs to the LCE family.	0.750
LCE1A	LCE3D	ENSP00000334869	ENSP00000357776	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3D; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.768
LCE1A	LCE4A	ENSP00000334869	ENSP00000357766	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 4A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.966
LCE1A	LCE5A	ENSP00000334869	ENSP00000333952	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 5A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.997
LCE1B	KRTAP9-2	ENSP00000353203	ENSP00000366950	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Keratin-associated protein 9-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.	0.951
LCE1B	LCE1A	ENSP00000353203	ENSP00000334869	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	0.977
LCE1B	LCE2A	ENSP00000353203	ENSP00000357768	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2A; Precursors of the cornified envelope of the stratum corneum.	0.993
LCE1B	LCE2B	ENSP00000353203	ENSP00000357769	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum.	0.995
LCE1B	LCE2C	ENSP00000353203	ENSP00000357772	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum.	0.993
LCE1B	LCE2D	ENSP00000353203	ENSP00000357773	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum.	0.994
LCE1B	LCE3A	ENSP00000353203	ENSP00000335006	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3A; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens ; Belongs to the LCE family.	0.977
LCE1B	LCE3D	ENSP00000353203	ENSP00000357776	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3D; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.983