Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LCE5ALate cornified envelope protein 5A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family. (118 aa)    
Predicted Functional Partners:
LCE1A
Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.
   
 0.997
LCE4A
Late cornified envelope protein 4A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.
   
 0.994
LCE1F
Late cornified envelope protein 1F; Precursors of the cornified envelope of the stratum corneum.
   
 0.992
LCE1C
Late cornified envelope protein 1C; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.
   
 0.991
LCE1E
Late cornified envelope protein 1E; Precursors of the cornified envelope of the stratum corneum.
   
 0.990
LCE1D
Late cornified envelope protein 1D; Precursors of the cornified envelope of the stratum corneum.
   
 
 0.986
LCE1B
Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.
   
 0.906
LCE2C
Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum.
   
 0.900
LCE2B
Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum.
   
 0.895
KRTAP4-12
Keratin associated protein 4-12.
    
   0.839
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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