LCE6A protein (human) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

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[Homology]

Score

LCE6A

Late cornified envelope protein 6A; Precursors of the cornified envelope of the stratum corneum. Belongs to the LCE family. (80 aa)

Predicted Functional Partners:

LCE2D

0.996

LCE2B

0.995

LCE1A

0.971

LCE2C

0.963

LCE2A

0.851

LCE1F

0.842

LCE1D

0.830

LCE1C

0.810

LCE3C

0.802

LCE1B

0.802

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LCE1A	LCE1B	ENSP00000334869	ENSP00000353203	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	0.977
LCE1A	LCE1C	ENSP00000334869	ENSP00000475270	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1C; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.995
LCE1A	LCE1D	ENSP00000334869	ENSP00000316737	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1D; Precursors of the cornified envelope of the stratum corneum.	0.992
LCE1A	LCE1F	ENSP00000334869	ENSP00000334187	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1F; Precursors of the cornified envelope of the stratum corneum.	0.994
LCE1A	LCE2A	ENSP00000334869	ENSP00000357768	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2A; Precursors of the cornified envelope of the stratum corneum.	0.920
LCE1A	LCE2B	ENSP00000334869	ENSP00000357769	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum.	0.997
LCE1A	LCE2C	ENSP00000334869	ENSP00000357772	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum.	0.987
LCE1A	LCE2D	ENSP00000334869	ENSP00000357773	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum.	0.996
LCE1A	LCE3C	ENSP00000334869	ENSP00000334644	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3C; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens.	0.935
LCE1A	LCE6A	ENSP00000334869	ENSP00000411070	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 6A; Precursors of the cornified envelope of the stratum corneum. Belongs to the LCE family.	0.971
LCE1B	LCE1A	ENSP00000353203	ENSP00000334869	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	0.977
LCE1B	LCE1C	ENSP00000353203	ENSP00000475270	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1C; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.980
LCE1B	LCE1D	ENSP00000353203	ENSP00000316737	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1D; Precursors of the cornified envelope of the stratum corneum.	0.932
LCE1B	LCE1F	ENSP00000353203	ENSP00000334187	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1F; Precursors of the cornified envelope of the stratum corneum.	0.903
LCE1B	LCE2A	ENSP00000353203	ENSP00000357768	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2A; Precursors of the cornified envelope of the stratum corneum.	0.993
LCE1B	LCE2B	ENSP00000353203	ENSP00000357769	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum.	0.995
LCE1B	LCE2C	ENSP00000353203	ENSP00000357772	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum.	0.993
LCE1B	LCE2D	ENSP00000353203	ENSP00000357773	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum.	0.994
LCE1B	LCE3C	ENSP00000353203	ENSP00000334644	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3C; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens.	0.877
LCE1B	LCE6A	ENSP00000353203	ENSP00000411070	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 6A; Precursors of the cornified envelope of the stratum corneum. Belongs to the LCE family.	0.802