| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADGRG7 | LDLRAD1 | ENSP00000273352 | ENSP00000360411 | Adhesion G-protein coupled receptor G7; Orphan receptor. | Low density lipoprotein receptor class A domain containing 1. | 0.788 |
| CLPB | LDLRAD1 | ENSP00000294053 | ENSP00000360411 | Caseinolytic peptidase B protein homolog; May function as a regulatory ATPase and be related to secretion/protein trafficking process. | Low density lipoprotein receptor class A domain containing 1. | 0.559 |
| CLPB | TMEM59 | ENSP00000294053 | ENSP00000234831 | Caseinolytic peptidase B protein homolog; May function as a regulatory ATPase and be related to secretion/protein trafficking process. | Transmembrane protein 59; Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding ; Belongs to the TMEM59 family. | 0.580 |
| LDLRAD1 | ADGRG7 | ENSP00000360411 | ENSP00000273352 | Low density lipoprotein receptor class A domain containing 1. | Adhesion G-protein coupled receptor G7; Orphan receptor. | 0.788 |
| LDLRAD1 | CLPB | ENSP00000360411 | ENSP00000294053 | Low density lipoprotein receptor class A domain containing 1. | Caseinolytic peptidase B protein homolog; May function as a regulatory ATPase and be related to secretion/protein trafficking process. | 0.559 |
| LDLRAD1 | LRRC42 | ENSP00000360411 | ENSP00000360421 | Low density lipoprotein receptor class A domain containing 1. | Leucine-rich repeat-containing protein 42; Leucine rich repeat containing 42; Belongs to the LRRC42 family. | 0.630 |
| LDLRAD1 | OLFM4 | ENSP00000360411 | ENSP00000219022 | Low density lipoprotein receptor class A domain containing 1. | Olfactomedin-4; May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin. | 0.603 |
| LDLRAD1 | SLC1A1 | ENSP00000360411 | ENSP00000262352 | Low density lipoprotein receptor class A domain containing 1. | Excitatory amino acid transporter 3; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays an important role in L-glutamate and L-aspartate reabsorptio [...] | 0.600 |
| LDLRAD1 | SNTN | ENSP00000360411 | ENSP00000341442 | Low density lipoprotein receptor class A domain containing 1. | Sentan; May be a component of the linker structure that bridges the ciliary membrane and peripheral singlet microtubules. | 0.714 |
| LDLRAD1 | TCEANC2 | ENSP00000360411 | ENSP00000234827 | Low density lipoprotein receptor class A domain containing 1. | Transcription elongation factor A N-terminal and central domain containing 2. | 0.660 |
| LDLRAD1 | TMEM190 | ENSP00000360411 | ENSP00000291934 | Low density lipoprotein receptor class A domain containing 1. | Transmembrane protein 190. | 0.649 |
| LDLRAD1 | TMEM218 | ENSP00000360411 | ENSP00000436596 | Low density lipoprotein receptor class A domain containing 1. | Transmembrane protein 218; May be involved in ciliary biogenesis or function. | 0.770 |
| LDLRAD1 | TMEM59 | ENSP00000360411 | ENSP00000234831 | Low density lipoprotein receptor class A domain containing 1. | Transmembrane protein 59; Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding ; Belongs to the TMEM59 family. | 0.664 |
| LRRC42 | LDLRAD1 | ENSP00000360421 | ENSP00000360411 | Leucine-rich repeat-containing protein 42; Leucine rich repeat containing 42; Belongs to the LRRC42 family. | Low density lipoprotein receptor class A domain containing 1. | 0.630 |
| LRRC42 | TCEANC2 | ENSP00000360421 | ENSP00000234827 | Leucine-rich repeat-containing protein 42; Leucine rich repeat containing 42; Belongs to the LRRC42 family. | Transcription elongation factor A N-terminal and central domain containing 2. | 0.651 |
| LRRC42 | TMEM59 | ENSP00000360421 | ENSP00000234831 | Leucine-rich repeat-containing protein 42; Leucine rich repeat containing 42; Belongs to the LRRC42 family. | Transmembrane protein 59; Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding ; Belongs to the TMEM59 family. | 0.479 |
| OLFM4 | LDLRAD1 | ENSP00000219022 | ENSP00000360411 | Olfactomedin-4; May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin. | Low density lipoprotein receptor class A domain containing 1. | 0.603 |
| SLC1A1 | LDLRAD1 | ENSP00000262352 | ENSP00000360411 | Excitatory amino acid transporter 3; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays an important role in L-glutamate and L-aspartate reabsorptio [...] | Low density lipoprotein receptor class A domain containing 1. | 0.600 |
| SNTN | LDLRAD1 | ENSP00000341442 | ENSP00000360411 | Sentan; May be a component of the linker structure that bridges the ciliary membrane and peripheral singlet microtubules. | Low density lipoprotein receptor class A domain containing 1. | 0.714 |
| SNTN | TMEM190 | ENSP00000341442 | ENSP00000291934 | Sentan; May be a component of the linker structure that bridges the ciliary membrane and peripheral singlet microtubules. | Transmembrane protein 190. | 0.444 |