LRIT2 protein (human) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Score

LRIT2

Leucine rich repeat, Ig-like and transmembrane domains 2. (560 aa)

Predicted Functional Partners:

LRIT1

0.795

MANSC4

0.637

LACTBL1

0.587

CCDC126

0.585

SAPCD1

0.569

CDHR1

0.559

WDR17

0.535

FAM169A

0.530

C10orf99

0.529

PPEF2

0.523

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C10orf99	LRIT1	ENSP00000361199	ENSP00000361177	Protein GPR15L; Chemotactic factor that mediates lymphocytes recruitment to epithelia through binding and activation of the G-protein coupled receptor GPR15. May be a tumor suppressor; together with SUSD2 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest.	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1; Possible role in phototransduction.	0.400
C10orf99	LRIT2	ENSP00000361199	ENSP00000438264	Protein GPR15L; Chemotactic factor that mediates lymphocytes recruitment to epithelia through binding and activation of the G-protein coupled receptor GPR15. May be a tumor suppressor; together with SUSD2 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest.	Leucine rich repeat, Ig-like and transmembrane domains 2.	0.529
CCDC126	FAM169A	ENSP00000304355	ENSP00000373808	Coiled-coil domain containing 126.	Soluble lamin-associated protein of 75 kDa; Family with sequence similarity 169 member A; Belongs to the FAM169 family.	0.503
CCDC126	LRIT2	ENSP00000304355	ENSP00000438264	Coiled-coil domain containing 126.	Leucine rich repeat, Ig-like and transmembrane domains 2.	0.585
CCDC126	WDR17	ENSP00000304355	ENSP00000280190	Coiled-coil domain containing 126.	WD repeat domain 17.	0.513
CDHR1	LRIT1	ENSP00000485478	ENSP00000361177	Cadherin-related family member 1; Potential calcium-dependent cell-adhesion protein. May be required for the structural integrity of the outer segment (OS) of photoreceptor cells (By similarity).	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1; Possible role in phototransduction.	0.575
CDHR1	LRIT2	ENSP00000485478	ENSP00000438264	Cadherin-related family member 1; Potential calcium-dependent cell-adhesion protein. May be required for the structural integrity of the outer segment (OS) of photoreceptor cells (By similarity).	Leucine rich repeat, Ig-like and transmembrane domains 2.	0.559
FAM169A	CCDC126	ENSP00000373808	ENSP00000304355	Soluble lamin-associated protein of 75 kDa; Family with sequence similarity 169 member A; Belongs to the FAM169 family.	Coiled-coil domain containing 126.	0.503
FAM169A	LRIT2	ENSP00000373808	ENSP00000438264	Soluble lamin-associated protein of 75 kDa; Family with sequence similarity 169 member A; Belongs to the FAM169 family.	Leucine rich repeat, Ig-like and transmembrane domains 2.	0.530
FAM169A	WDR17	ENSP00000373808	ENSP00000280190	Soluble lamin-associated protein of 75 kDa; Family with sequence similarity 169 member A; Belongs to the FAM169 family.	WD repeat domain 17.	0.494
LACTBL1	LRIT2	ENSP00000402297	ENSP00000438264	Putative beta-lactamase-like 1; Lactamase beta like 1; Belongs to the beta-lactamase family.	Leucine rich repeat, Ig-like and transmembrane domains 2.	0.587
LACTBL1	SAPCD1	ENSP00000402297	ENSP00000411948	Putative beta-lactamase-like 1; Lactamase beta like 1; Belongs to the beta-lactamase family.	Suppressor APC domain containing 1.	0.469
LRIT1	C10orf99	ENSP00000361177	ENSP00000361199	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1; Possible role in phototransduction.	Protein GPR15L; Chemotactic factor that mediates lymphocytes recruitment to epithelia through binding and activation of the G-protein coupled receptor GPR15. May be a tumor suppressor; together with SUSD2 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest.	0.400
LRIT1	CDHR1	ENSP00000361177	ENSP00000485478	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1; Possible role in phototransduction.	Cadherin-related family member 1; Potential calcium-dependent cell-adhesion protein. May be required for the structural integrity of the outer segment (OS) of photoreceptor cells (By similarity).	0.575
LRIT1	LRIT2	ENSP00000361177	ENSP00000438264	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1; Possible role in phototransduction.	Leucine rich repeat, Ig-like and transmembrane domains 2.	0.795
LRIT1	MANSC4	ENSP00000361177	ENSP00000370673	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1; Possible role in phototransduction.	MANSC domain containing 4.	0.605
LRIT1	PPEF2	ENSP00000361177	ENSP00000286719	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1; Possible role in phototransduction.	Serine/threonine-protein phosphatase with EF-hands 2; May play a role in phototransduction. May dephosphorylate photoactivated rhodopsin. May function as a calcium sensing regulator of ionic currents, energy production or synaptic transmission.	0.418
LRIT1	WDR17	ENSP00000361177	ENSP00000280190	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1; Possible role in phototransduction.	WD repeat domain 17.	0.405
LRIT2	C10orf99	ENSP00000438264	ENSP00000361199	Leucine rich repeat, Ig-like and transmembrane domains 2.	Protein GPR15L; Chemotactic factor that mediates lymphocytes recruitment to epithelia through binding and activation of the G-protein coupled receptor GPR15. May be a tumor suppressor; together with SUSD2 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest.	0.529
LRIT2	CCDC126	ENSP00000438264	ENSP00000304355	Leucine rich repeat, Ig-like and transmembrane domains 2.	Coiled-coil domain containing 126.	0.585