LRRC37A protein (human) - STRING interaction network

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Score

LRRC37A

Leucine-rich repeat-containing protein 37A; Leucine rich repeat containing 37A. (1700 aa)

Predicted Functional Partners:

LRRC37A2

0.946

LRRC37A3

0.940

LRRC37B

0.870

ARL17B

0.761

ARL17A

0.755

KANSL1

0.744

POTEB

0.592

FAM71B

0.572

CRHR1

0.549

ARHGAP27

0.547

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP27	ARL17A	ENSP00000403323	ENSP00000337478	Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).	ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity).	0.562
ARHGAP27	ARL17B	ENSP00000403323	ENSP00000460539	Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).	ADP-ribosylation factor-like protein 17; ADP ribosylation factor like GTPase 17B.	0.560
ARHGAP27	CRHR1	ENSP00000403323	ENSP00000381333	Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).	Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...]	0.508
ARHGAP27	KANSL1	ENSP00000403323	ENSP00000387393	Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).	KAT8 regulatory NSL complex subunit 1; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.	0.619
ARHGAP27	LRRC37A	ENSP00000403323	ENSP00000326324	Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).	Leucine-rich repeat-containing protein 37A; Leucine rich repeat containing 37A.	0.547
ARHGAP27	LRRC37A2	ENSP00000403323	ENSP00000459551	Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).	Leucine-rich repeat-containing protein 37A2; Leucine rich repeat containing 37 member A2.	0.569
ARHGAP27	LRRC37A3	ENSP00000403323	ENSP00000464535	Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).	Leucine-rich repeat-containing protein 37A3; Leucine rich repeat containing 37 member A3.	0.540
ARL17A	ARHGAP27	ENSP00000337478	ENSP00000403323	ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity).	Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).	0.562
ARL17A	CRHR1	ENSP00000337478	ENSP00000381333	ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity).	Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...]	0.443
ARL17A	KANSL1	ENSP00000337478	ENSP00000387393	ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity).	KAT8 regulatory NSL complex subunit 1; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.	0.758
ARL17A	LRRC37A	ENSP00000337478	ENSP00000326324	ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity).	Leucine-rich repeat-containing protein 37A; Leucine rich repeat containing 37A.	0.755
ARL17A	LRRC37A2	ENSP00000337478	ENSP00000459551	ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity).	Leucine-rich repeat-containing protein 37A2; Leucine rich repeat containing 37 member A2.	0.761
ARL17A	LRRC37A3	ENSP00000337478	ENSP00000464535	ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity).	Leucine-rich repeat-containing protein 37A3; Leucine rich repeat containing 37 member A3.	0.759
ARL17B	ARHGAP27	ENSP00000460539	ENSP00000403323	ADP-ribosylation factor-like protein 17; ADP ribosylation factor like GTPase 17B.	Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).	0.560
ARL17B	CRHR1	ENSP00000460539	ENSP00000381333	ADP-ribosylation factor-like protein 17; ADP ribosylation factor like GTPase 17B.	Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...]	0.433
ARL17B	KANSL1	ENSP00000460539	ENSP00000387393	ADP-ribosylation factor-like protein 17; ADP ribosylation factor like GTPase 17B.	KAT8 regulatory NSL complex subunit 1; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.	0.756
ARL17B	LRRC37A	ENSP00000460539	ENSP00000326324	ADP-ribosylation factor-like protein 17; ADP ribosylation factor like GTPase 17B.	Leucine-rich repeat-containing protein 37A; Leucine rich repeat containing 37A.	0.761
ARL17B	LRRC37A2	ENSP00000460539	ENSP00000459551	ADP-ribosylation factor-like protein 17; ADP ribosylation factor like GTPase 17B.	Leucine-rich repeat-containing protein 37A2; Leucine rich repeat containing 37 member A2.	0.785
ARL17B	LRRC37A3	ENSP00000460539	ENSP00000464535	ADP-ribosylation factor-like protein 17; ADP ribosylation factor like GTPase 17B.	Leucine-rich repeat-containing protein 37A3; Leucine rich repeat containing 37 member A3.	0.766
ARL17B	POTEB	ENSP00000460539	ENSP00000457689	ADP-ribosylation factor-like protein 17; ADP ribosylation factor like GTPase 17B.	POTE ankyrin domain family member B.	0.558