Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
LRRC37BLeucine-rich repeat-containing protein 37B; Leucine rich repeat containing 37B. (947 aa)    
Predicted Functional Partners:
LRRC37A
Leucine-rich repeat-containing protein 37A; Leucine rich repeat containing 37A.
  
  
0.870
LRRC37A2
Leucine-rich repeat-containing protein 37A2; Leucine rich repeat containing 37 member A2.
  
  
0.870
LRRC37A3
Leucine-rich repeat-containing protein 37A3; Leucine rich repeat containing 37 member A3.
  
  
0.859
FAM71B
Protein FAM71B; May be involved in RNA biogenesis.
   
    0.730
UTP6
U3 small nucleolar RNA-associated protein 6 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the UTP6 family.
   
  
 0.713
CRLF3
Cytokine receptor-like factor 3; May play a role in the negative regulation of cell cycle progression.
   
  
 0.709
AKAP3
A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction.
   
  
 0.680
SPESP1
Sperm equatorial segment protein 1; Involved in fertilization ability of sperm. Belongs to the SPESP1 family.
   
  
 0.654
AKAP4
A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family.
   
  
 0.651
ADAP2
Arf-GAP with dual PH domain-containing protein 2; GTPase-activating protein for the ADP ribosylation factor family (Potential). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). Possesses a stoichiometry of two binding sites for InsP4 with identical affinity.
      
 0.651
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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