Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LY6G6CLymphocyte antigen 6 family member G6C. (125 aa)    
Predicted Functional Partners:
LY6G6E
Lymphocyte antigen 6 family member G6E.
   
  
 0.766
LY6G6D
Lymphocyte antigen 6 family member G6D.
   
 
 0.722
SLC39A2
Zinc transporter ZIP2; Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis.
   
 
 0.679
LY6G6F
Lymphocyte antigen 6 complex locus protein G6f; May play a role in the downstream signal transduction pathways involving GRB2 and GRB7.
   
  
 0.661
LY6G5B
Lymphocyte antigen 6 family member G5B.
   
  
 0.660
LY6G5C
Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation.
   
  
 0.611
LY6L
Lymphocyte antigen 6 family member L.
      
 0.574
MPIG6B
Megakaryocyte and platelet inhibitory receptor G6b; Inhibitory receptor that acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production. Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide. This regulation of megakaryocate function as well as platelet production ann activation is done through the inhibition (via the 2 ITIM motifs) of the receptors CLEC1B and GP6:FcRgamma signaling. Appears to operate in a calcium-independent manner.
   
  
 0.564
PATE3
Prostate and testis expressed 3; Belongs to the PATE family.
      
 0.547
VWA7
Von Willebrand factor A domain containing 7.
   
  
 0.514
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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