| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DCD | LACRT | ENSP00000406773 | ENSP00000257867 | Survival-promoting peptide; DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity, cleaving on the C- terminal side of Arg and, to a lesser extent, Lys residues. | Extracellular glycoprotein lacritin; Modulates secretion by lacrimal acinar cells. | 0.629 |
| DCD | LCN1 | ENSP00000406773 | ENSP00000263598 | Survival-promoting peptide; DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity, cleaving on the C- terminal side of Arg and, to a lesser extent, Lys residues. | Lipocalin-1; Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket; Belongs to the calycin superfamily. Lipocalin family. | 0.622 |
| DCD | LTF | ENSP00000406773 | ENSP00000231751 | Survival-promoting peptide; DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity, cleaving on the C- terminal side of Arg and, to a lesser extent, Lys residues. | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactoferricin binds to the bacterial surface and is crucial for the bactericidal functions. Has some antiviral activity against papillomavirus infection. N-terminal region shows strong antifungal activity against C.albicans. Contains two BBXB heparin-binding consensus sequences that appear to form the predominate functional GAG- binding site. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows pr [...] | 0.473 |
| DCD | LYZL1 | ENSP00000406773 | ENSP00000364650 | Survival-promoting peptide; DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity, cleaving on the C- terminal side of Arg and, to a lesser extent, Lys residues. | Lysozyme-like protein 1; Lysozyme like 1; Belongs to the glycosyl hydrolase 22 family. | 0.535 |
| DCD | PIP | ENSP00000406773 | ENSP00000291009 | Survival-promoting peptide; DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity, cleaving on the C- terminal side of Arg and, to a lesser extent, Lys residues. | Prolactin induced protein; Belongs to the PIP family. | 0.546 |
| GKN1 | LYZL1 | ENSP00000501093 | ENSP00000364650 | Gastrokine-1; Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium. | Lysozyme-like protein 1; Lysozyme like 1; Belongs to the glycosyl hydrolase 22 family. | 0.547 |
| LACRT | DCD | ENSP00000257867 | ENSP00000406773 | Extracellular glycoprotein lacritin; Modulates secretion by lacrimal acinar cells. | Survival-promoting peptide; DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity, cleaving on the C- terminal side of Arg and, to a lesser extent, Lys residues. | 0.629 |
| LACRT | LCN1 | ENSP00000257867 | ENSP00000263598 | Extracellular glycoprotein lacritin; Modulates secretion by lacrimal acinar cells. | Lipocalin-1; Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket; Belongs to the calycin superfamily. Lipocalin family. | 0.826 |
| LACRT | LTF | ENSP00000257867 | ENSP00000231751 | Extracellular glycoprotein lacritin; Modulates secretion by lacrimal acinar cells. | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactoferricin binds to the bacterial surface and is crucial for the bactericidal functions. Has some antiviral activity against papillomavirus infection. N-terminal region shows strong antifungal activity against C.albicans. Contains two BBXB heparin-binding consensus sequences that appear to form the predominate functional GAG- binding site. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows pr [...] | 0.613 |
| LACRT | LYZL1 | ENSP00000257867 | ENSP00000364650 | Extracellular glycoprotein lacritin; Modulates secretion by lacrimal acinar cells. | Lysozyme-like protein 1; Lysozyme like 1; Belongs to the glycosyl hydrolase 22 family. | 0.654 |
| LACRT | PIP | ENSP00000257867 | ENSP00000291009 | Extracellular glycoprotein lacritin; Modulates secretion by lacrimal acinar cells. | Prolactin induced protein; Belongs to the PIP family. | 0.564 |
| LACRT | PRR4 | ENSP00000257867 | ENSP00000228811 | Extracellular glycoprotein lacritin; Modulates secretion by lacrimal acinar cells. | Proline-rich protein 4; Proline rich 4. | 0.674 |
| LACRT | SCGB1D1 | ENSP00000257867 | ENSP00000303070 | Extracellular glycoprotein lacritin; Modulates secretion by lacrimal acinar cells. | Secretoglobin family 1D member 1; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones. | 0.870 |
| LCN1 | DCD | ENSP00000263598 | ENSP00000406773 | Lipocalin-1; Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket; Belongs to the calycin superfamily. Lipocalin family. | Survival-promoting peptide; DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity, cleaving on the C- terminal side of Arg and, to a lesser extent, Lys residues. | 0.622 |
| LCN1 | LACRT | ENSP00000263598 | ENSP00000257867 | Lipocalin-1; Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket; Belongs to the calycin superfamily. Lipocalin family. | Extracellular glycoprotein lacritin; Modulates secretion by lacrimal acinar cells. | 0.826 |
| LCN1 | LTF | ENSP00000263598 | ENSP00000231751 | Lipocalin-1; Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket; Belongs to the calycin superfamily. Lipocalin family. | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactoferricin binds to the bacterial surface and is crucial for the bactericidal functions. Has some antiviral activity against papillomavirus infection. N-terminal region shows strong antifungal activity against C.albicans. Contains two BBXB heparin-binding consensus sequences that appear to form the predominate functional GAG- binding site. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows pr [...] | 0.713 |
| LCN1 | LYZL1 | ENSP00000263598 | ENSP00000364650 | Lipocalin-1; Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket; Belongs to the calycin superfamily. Lipocalin family. | Lysozyme-like protein 1; Lysozyme like 1; Belongs to the glycosyl hydrolase 22 family. | 0.721 |
| LCN1 | PIP | ENSP00000263598 | ENSP00000291009 | Lipocalin-1; Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket; Belongs to the calycin superfamily. Lipocalin family. | Prolactin induced protein; Belongs to the PIP family. | 0.692 |
| LCN1 | PRR4 | ENSP00000263598 | ENSP00000228811 | Lipocalin-1; Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket; Belongs to the calycin superfamily. Lipocalin family. | Proline-rich protein 4; Proline rich 4. | 0.784 |
| LCN1 | SCGB1D1 | ENSP00000263598 | ENSP00000303070 | Lipocalin-1; Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket; Belongs to the calycin superfamily. Lipocalin family. | Secretoglobin family 1D member 1; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones. | 0.720 |