METTL15 protein (human) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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experimentally determined

co-expression

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gene neighborhood

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[Homology]

Score

METTL15

Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase. (407 aa)

Predicted Functional Partners:

RBFA

0.966

MRPS7

0.933

MRPS11

0.933

DAP3

0.909

MRPS9

0.895

NOA1

0.884

MRPS16

0.879

PUS1

0.868

MRPS6

0.867

MRPS2

0.863

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAP3	METTL15	ENSP00000357320	ENSP00000384369	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family.	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	0.909
DAP3	MRPS11	ENSP00000357320	ENSP00000317376	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family.	Mitochondrial ribosomal protein S11.	0.999
DAP3	MRPS16	ENSP00000357320	ENSP00000362036	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family.	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.999
DAP3	MRPS2	ENSP00000357320	ENSP00000360850	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family.	28S ribosomal protein S2, mitochondrial; Required for mitoribosome formation and stability, and mitochondrial translation; Belongs to the universal ribosomal protein uS2 family.	0.999
DAP3	MRPS6	ENSP00000357320	ENSP00000382250	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family.	Mitochondrial ribosomal protein S6.	0.997
DAP3	MRPS7	ENSP00000357320	ENSP00000245539	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family.	Mitochondrial ribosomal protein S7.	0.999
DAP3	MRPS9	ENSP00000357320	ENSP00000258455	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family.	Mitochondrial ribosomal protein S9.	0.999
DAP3	NOA1	ENSP00000357320	ENSP00000264230	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family.	Nitric oxide-associated protein 1; Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP; Belongs to the TRAFAC class YlqF/YawG GTPase family. NOA1 subfamily.	0.965
DAP3	PUS1	ENSP00000357320	ENSP00000365837	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family.	tRNA pseudouridine synthase A; Converts specific uridines to PSI in a number of tRNA substrates. Acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Involved in regulation of nuclear receptor activity through pseudouridylation of SRA1 RNA; Belongs to the tRNA pseudouridine synthase TruA family.	0.865
DAP3	RBFA	ENSP00000357320	ENSP00000305696	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family.	Putative ribosome-binding factor A, mitochondrial; Ribosome binding factor A.	0.838
METTL15	DAP3	ENSP00000384369	ENSP00000357320	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family.	0.909
METTL15	MRPS11	ENSP00000384369	ENSP00000317376	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Mitochondrial ribosomal protein S11.	0.933
METTL15	MRPS16	ENSP00000384369	ENSP00000362036	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.879
METTL15	MRPS2	ENSP00000384369	ENSP00000360850	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	28S ribosomal protein S2, mitochondrial; Required for mitoribosome formation and stability, and mitochondrial translation; Belongs to the universal ribosomal protein uS2 family.	0.863
METTL15	MRPS6	ENSP00000384369	ENSP00000382250	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Mitochondrial ribosomal protein S6.	0.867
METTL15	MRPS7	ENSP00000384369	ENSP00000245539	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Mitochondrial ribosomal protein S7.	0.933
METTL15	MRPS9	ENSP00000384369	ENSP00000258455	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Mitochondrial ribosomal protein S9.	0.895
METTL15	NOA1	ENSP00000384369	ENSP00000264230	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Nitric oxide-associated protein 1; Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP; Belongs to the TRAFAC class YlqF/YawG GTPase family. NOA1 subfamily.	0.884
METTL15	PUS1	ENSP00000384369	ENSP00000365837	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	tRNA pseudouridine synthase A; Converts specific uridines to PSI in a number of tRNA substrates. Acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Involved in regulation of nuclear receptor activity through pseudouridylation of SRA1 RNA; Belongs to the tRNA pseudouridine synthase TruA family.	0.868
METTL15	RBFA	ENSP00000384369	ENSP00000305696	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Putative ribosome-binding factor A, mitochondrial; Ribosome binding factor A.	0.966