MRPL10 protein (human) - STRING interaction network

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Score

MRPL10

Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family. (271 aa)

Predicted Functional Partners:

MRPL44

0.999

MRPL16

0.999

MRPL58

0.999

MRPL13

0.999

MRPL4

0.999

MRPL11

0.999

MRPL1

0.999

GADD45GIP1

0.999

MRPL12

0.999

MRPL52

0.999

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GADD45GIP1	MRPL1	ENSP00000323065	ENSP00000315017	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L1.	0.881
GADD45GIP1	MRPL10	ENSP00000323065	ENSP00000290208	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family.	0.999
GADD45GIP1	MRPL11	ENSP00000323065	ENSP00000308897	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.	0.999
GADD45GIP1	MRPL12	ENSP00000323065	ENSP00000333837	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family.	0.988
GADD45GIP1	MRPL13	ENSP00000323065	ENSP00000306548	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.	0.999
GADD45GIP1	MRPL16	ENSP00000323065	ENSP00000300151	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family.	0.994
GADD45GIP1	MRPL4	ENSP00000323065	ENSP00000306902	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	0.999
GADD45GIP1	MRPL44	ENSP00000323065	ENSP00000258383	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome.	0.993
GADD45GIP1	MRPL52	ENSP00000323065	ENSP00000347277	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L52.	0.999
GADD45GIP1	MRPL58	ENSP00000323065	ENSP00000301585	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.	0.999
MRPL1	GADD45GIP1	ENSP00000315017	ENSP00000323065	Mitochondrial ribosomal protein L1.	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	0.881
MRPL1	MRPL10	ENSP00000315017	ENSP00000290208	Mitochondrial ribosomal protein L1.	Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family.	0.999
MRPL1	MRPL11	ENSP00000315017	ENSP00000308897	Mitochondrial ribosomal protein L1.	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.	0.993
MRPL1	MRPL12	ENSP00000315017	ENSP00000333837	Mitochondrial ribosomal protein L1.	39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family.	0.998
MRPL1	MRPL13	ENSP00000315017	ENSP00000306548	Mitochondrial ribosomal protein L1.	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.	0.999
MRPL1	MRPL16	ENSP00000315017	ENSP00000300151	Mitochondrial ribosomal protein L1.	Mitochondrial ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family.	0.970
MRPL1	MRPL4	ENSP00000315017	ENSP00000306902	Mitochondrial ribosomal protein L1.	Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	0.999
MRPL1	MRPL44	ENSP00000315017	ENSP00000258383	Mitochondrial ribosomal protein L1.	39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome.	0.943
MRPL1	MRPL52	ENSP00000315017	ENSP00000347277	Mitochondrial ribosomal protein L1.	Mitochondrial ribosomal protein L52.	0.999
MRPL1	MRPL58	ENSP00000315017	ENSP00000301585	Mitochondrial ribosomal protein L1.	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.	0.888