Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MRPL43Mitochondrial ribosomal protein L43. (235 aa)    
Predicted Functional Partners:
MRPL44
39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome.
   
 
 0.999
MRPL20
Mitochondrial ribosomal protein L20.
   
 
 0.999
MRPL47
Mitochondrial ribosomal protein L47; Belongs to the universal ribosomal protein uL29 family.
   
 
 0.999
MRPL4
Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.
   
 
 0.997
MRPL13
Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.
   
 
 0.996
MRPL42
Mitochondrial ribosomal protein L42; Belongs to the mitochondrion-specific ribosomal protein mL42 family.
   
 
 0.996
MRPS10
Mitochondrial ribosomal protein S10; Belongs to the universal ribosomal protein uS10 family.
   
 
 0.995
MRPL49
Mitochondrial ribosomal protein L49.
   
 
 0.995
MALSU1
Mitochondrial assembly of ribosomal large subunit protein 1; Required for normal mitochondrial ribosome function and mitochondrial translation. May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable). Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable). Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of [...]
   
  0.995
MRPL10
Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family.
   
 
 0.994
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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