MRPL53 protein (human) - STRING interaction network

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Score

MRPL53

Mitochondrial ribosomal protein L53. (112 aa)

Predicted Functional Partners:

MRPL11

0.999

MRPL12

0.999

MRPL52

0.999

MRPS18A

0.999

MRPS30

0.999

MRPL50

0.995

GADD45GIP1

0.986

MRPL10

0.982

MRPL2

0.977

NDUFAB1

0.973

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GADD45GIP1	MRPL10	ENSP00000323065	ENSP00000290208	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family.	0.999
GADD45GIP1	MRPL11	ENSP00000323065	ENSP00000308897	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.	0.999
GADD45GIP1	MRPL12	ENSP00000323065	ENSP00000333837	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family.	0.988
GADD45GIP1	MRPL2	ENSP00000323065	ENSP00000373404	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L2; Belongs to the universal ribosomal protein uL2 family.	0.999
GADD45GIP1	MRPL50	ENSP00000323065	ENSP00000363999	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L50.	0.999
GADD45GIP1	MRPL52	ENSP00000323065	ENSP00000347277	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L52.	0.999
GADD45GIP1	MRPL53	ENSP00000323065	ENSP00000258105	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L53.	0.986
GADD45GIP1	MRPS18A	ENSP00000323065	ENSP00000361206	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein S18A; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mL66 subfamily.	0.993
GADD45GIP1	MRPS30	ENSP00000323065	ENSP00000424328	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein S30.	0.999
GADD45GIP1	NDUFAB1	ENSP00000323065	ENSP00000458770	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Acyl carrier protein, mitochondrial; Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity). Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain.	0.983
MRPL10	GADD45GIP1	ENSP00000290208	ENSP00000323065	Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family.	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	0.999
MRPL10	MRPL11	ENSP00000290208	ENSP00000308897	Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family.	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.	0.999
MRPL10	MRPL12	ENSP00000290208	ENSP00000333837	Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family.	39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family.	0.999
MRPL10	MRPL2	ENSP00000290208	ENSP00000373404	Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family.	Mitochondrial ribosomal protein L2; Belongs to the universal ribosomal protein uL2 family.	0.995
MRPL10	MRPL50	ENSP00000290208	ENSP00000363999	Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family.	Mitochondrial ribosomal protein L50.	0.999
MRPL10	MRPL52	ENSP00000290208	ENSP00000347277	Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family.	Mitochondrial ribosomal protein L52.	0.999
MRPL10	MRPL53	ENSP00000290208	ENSP00000258105	Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family.	Mitochondrial ribosomal protein L53.	0.982
MRPL10	MRPS18A	ENSP00000290208	ENSP00000361206	Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family.	Mitochondrial ribosomal protein S18A; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mL66 subfamily.	0.998
MRPL10	MRPS30	ENSP00000290208	ENSP00000424328	Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family.	Mitochondrial ribosomal protein S30.	0.999
MRPL10	NDUFAB1	ENSP00000290208	ENSP00000458770	Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family.	Acyl carrier protein, mitochondrial; Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity). Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain.	0.971