| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARHGEF37 | BAIAP2L1 | ENSP00000328083 | ENSP00000005260 | Rho guanine nucleotide exchange factor 37; May act as a guanine nucleotide exchange factor (GEF). | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. | 0.400 |
| ARHGEF37 | FCHSD1 | ENSP00000328083 | ENSP00000399259 | Rho guanine nucleotide exchange factor 37; May act as a guanine nucleotide exchange factor (GEF). | F-BAR and double SH3 domains protein 1; Promotes actin polymerization mediated by SNX9 and WASL. | 0.580 |
| ARHGEF37 | MTSS2 | ENSP00000328083 | ENSP00000341171 | Rho guanine nucleotide exchange factor 37; May act as a guanine nucleotide exchange factor (GEF). | Protein MTSS 2; Involved in plasma membrane dynamics. Potentiated PDGF- mediated formation of membrane ruffles and lamellipodia in fibroblasts, acting via RAC1 activation. May function in actin bundling ; Belongs to the MTSS family. | 0.575 |
| ARHGEF38 | FCHSD1 | ENSP00000416125 | ENSP00000399259 | Rho guanine nucleotide exchange factor 38; May act as a guanine-nucleotide releasing factor. | F-BAR and double SH3 domains protein 1; Promotes actin polymerization mediated by SNX9 and WASL. | 0.507 |
| ARHGEF38 | MTSS2 | ENSP00000416125 | ENSP00000341171 | Rho guanine nucleotide exchange factor 38; May act as a guanine-nucleotide releasing factor. | Protein MTSS 2; Involved in plasma membrane dynamics. Potentiated PDGF- mediated formation of membrane ruffles and lamellipodia in fibroblasts, acting via RAC1 activation. May function in actin bundling ; Belongs to the MTSS family. | 0.475 |
| BAIAP2L1 | ARHGEF37 | ENSP00000005260 | ENSP00000328083 | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. | Rho guanine nucleotide exchange factor 37; May act as a guanine nucleotide exchange factor (GEF). | 0.400 |
| BAIAP2L1 | BAIAP2L2 | ENSP00000005260 | ENSP00000371085 | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2; Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) headgroups. There seems to be no clear preference for a specific phosphoinositide (By similarity). | 0.510 |
| BAIAP2L1 | FCHSD1 | ENSP00000005260 | ENSP00000399259 | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. | F-BAR and double SH3 domains protein 1; Promotes actin polymerization mediated by SNX9 and WASL. | 0.402 |
| BAIAP2L1 | MTSS2 | ENSP00000005260 | ENSP00000341171 | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. | Protein MTSS 2; Involved in plasma membrane dynamics. Potentiated PDGF- mediated formation of membrane ruffles and lamellipodia in fibroblasts, acting via RAC1 activation. May function in actin bundling ; Belongs to the MTSS family. | 0.572 |
| BAIAP2L2 | BAIAP2L1 | ENSP00000371085 | ENSP00000005260 | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2; Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) headgroups. There seems to be no clear preference for a specific phosphoinositide (By similarity). | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. | 0.510 |
| BAIAP2L2 | FCHSD1 | ENSP00000371085 | ENSP00000399259 | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2; Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) headgroups. There seems to be no clear preference for a specific phosphoinositide (By similarity). | F-BAR and double SH3 domains protein 1; Promotes actin polymerization mediated by SNX9 and WASL. | 0.435 |
| BAIAP2L2 | MTSS2 | ENSP00000371085 | ENSP00000341171 | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2; Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) headgroups. There seems to be no clear preference for a specific phosphoinositide (By similarity). | Protein MTSS 2; Involved in plasma membrane dynamics. Potentiated PDGF- mediated formation of membrane ruffles and lamellipodia in fibroblasts, acting via RAC1 activation. May function in actin bundling ; Belongs to the MTSS family. | 0.614 |
| DNMBP | FCHSD1 | ENSP00000315659 | ENSP00000399259 | Dynamin-binding protein; Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis (By similarity). May play a role in membrane trafficking between the cell surface and the Golgi (By similarity). ECO:0000250|UniProtKB:Q6TXD4. | F-BAR and double SH3 domains protein 1; Promotes actin polymerization mediated by SNX9 and WASL. | 0.551 |
| DNMBP | MTSS2 | ENSP00000315659 | ENSP00000341171 | Dynamin-binding protein; Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis (By similarity). May play a role in membrane trafficking between the cell surface and the Golgi (By similarity). ECO:0000250|UniProtKB:Q6TXD4. | Protein MTSS 2; Involved in plasma membrane dynamics. Potentiated PDGF- mediated formation of membrane ruffles and lamellipodia in fibroblasts, acting via RAC1 activation. May function in actin bundling ; Belongs to the MTSS family. | 0.467 |
| DNMBP | TRIM67 | ENSP00000315659 | ENSP00000355613 | Dynamin-binding protein; Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis (By similarity). May play a role in membrane trafficking between the cell surface and the Golgi (By similarity). ECO:0000250|UniProtKB:Q6TXD4. | Tripartite motif containing 67; Belongs to the TRIM/RBCC family. | 0.502 |
| FCHSD1 | ARHGEF37 | ENSP00000399259 | ENSP00000328083 | F-BAR and double SH3 domains protein 1; Promotes actin polymerization mediated by SNX9 and WASL. | Rho guanine nucleotide exchange factor 37; May act as a guanine nucleotide exchange factor (GEF). | 0.580 |
| FCHSD1 | ARHGEF38 | ENSP00000399259 | ENSP00000416125 | F-BAR and double SH3 domains protein 1; Promotes actin polymerization mediated by SNX9 and WASL. | Rho guanine nucleotide exchange factor 38; May act as a guanine-nucleotide releasing factor. | 0.507 |
| FCHSD1 | BAIAP2L1 | ENSP00000399259 | ENSP00000005260 | F-BAR and double SH3 domains protein 1; Promotes actin polymerization mediated by SNX9 and WASL. | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. | 0.402 |
| FCHSD1 | BAIAP2L2 | ENSP00000399259 | ENSP00000371085 | F-BAR and double SH3 domains protein 1; Promotes actin polymerization mediated by SNX9 and WASL. | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2; Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) headgroups. There seems to be no clear preference for a specific phosphoinositide (By similarity). | 0.435 |
| FCHSD1 | DNMBP | ENSP00000399259 | ENSP00000315659 | F-BAR and double SH3 domains protein 1; Promotes actin polymerization mediated by SNX9 and WASL. | Dynamin-binding protein; Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis (By similarity). May play a role in membrane trafficking between the cell surface and the Golgi (By similarity). ECO:0000250|UniProtKB:Q6TXD4. | 0.551 |
