Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NBPF3Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family. (633 aa)    
Predicted Functional Partners:
NBPF1
Neuroblastoma breakpoint family member 1; NBPF member 1; Belongs to the NBPF family.
   
 
0.899
NBPF11
Neuroblastoma breakpoint family member 11; NBPF member 11; Belongs to the NBPF family.
   
   
0.892
ALPL
Alkaline phosphatase, tissue-nonspecific isozyme; This isozyme plays a key role in skeletal mineralization by regulating levels of diphosphate (PPi); Belongs to the alkaline phosphatase family.
    
 
 0.867
NBPF15
Neuroblastoma breakpoint family member 15; NBPF member 15.
  
  
0.855
NBPF10
Neuroblastoma breakpoint family member 10; NBPF member 10.
   
  
0.853
NBPF20
Neuroblastoma breakpoint family member 20; NBPF member 20; Belongs to the NBPF family.
   
  
0.851
NBPF19-2
Neuroblastoma breakpoint family member 19; Belongs to the NBPF family.
   
  
0.847
NBPF12
Neuroblastoma breakpoint family member 12; NBPF member 12.
   
   
0.846
PRAMEF14
PRAME family member 14.
  
   
 0.643
TSEN15
tRNA-splicing endonuclease subunit Sen15; Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA bo [...]
   
   0.603
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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