| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABCG2 | PCDH7 | ENSP00000498246 | ENSP00000441802 | Broad substrate specificity ATP-binding cassette transporter ABCG2; Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes a wide variety of physiological compounds, dietary toxins and xenobiotics from cells. Involved in porphyrin homeostasis, mediating the export of protoporphyrin IX (PPIX) from both mitochondria to cytosol and cytosol to extracellular space, it also functions in the cellular export of heme. Also mediates the efflux of sphingosine-1-P from cells. Acts as a urate exporter functioning in both renal and extra [...] | Protocadherin-7; Protocadherin 7. | 0.646 |
| CCKAR | PCDH7 | ENSP00000295589 | ENSP00000441802 | Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. | Protocadherin-7; Protocadherin 7. | 0.781 |
| CCKAR | STIM2 | ENSP00000295589 | ENSP00000417569 | Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. | Stromal interaction molecule 2; Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRA [...] | 0.750 |
| FCGR1A | PCDH7 | ENSP00000358165 | ENSP00000441802 | High affinity immunoglobulin gamma Fc receptor I; High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. | Protocadherin-7; Protocadherin 7. | 0.849 |
| GTPBP1 | PCDH7 | ENSP00000216044 | ENSP00000441802 | GTP-binding protein 1; Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity (By similarity). | Protocadherin-7; Protocadherin 7. | 0.829 |
| GTPBP2 | PCDH7 | ENSP00000303997 | ENSP00000441802 | GTP binding protein 2. | Protocadherin-7; Protocadherin 7. | 0.830 |
| PCDH20-2 | PCDH7 | ENSP00000386653 | ENSP00000441802 | Protocadherin-20; Potential calcium-dependent cell-adhesion protein. | Protocadherin-7; Protocadherin 7. | 0.925 |
| PCDH20-2 | PCDHGB1 | ENSP00000386653 | ENSP00000429273 | Protocadherin-20; Potential calcium-dependent cell-adhesion protein. | Protocadherin gamma-B1; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. | 0.794 |
| PCDH20-2 | RRM2 | ENSP00000386653 | ENSP00000353770 | Protocadherin-20; Potential calcium-dependent cell-adhesion protein. | Ribonucleoside-diphosphate reductase subunit M2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.516 |
| PCDH7 | ABCG2 | ENSP00000441802 | ENSP00000498246 | Protocadherin-7; Protocadherin 7. | Broad substrate specificity ATP-binding cassette transporter ABCG2; Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes a wide variety of physiological compounds, dietary toxins and xenobiotics from cells. Involved in porphyrin homeostasis, mediating the export of protoporphyrin IX (PPIX) from both mitochondria to cytosol and cytosol to extracellular space, it also functions in the cellular export of heme. Also mediates the efflux of sphingosine-1-P from cells. Acts as a urate exporter functioning in both renal and extra [...] | 0.646 |
| PCDH7 | CCKAR | ENSP00000441802 | ENSP00000295589 | Protocadherin-7; Protocadherin 7. | Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. | 0.781 |
| PCDH7 | FCGR1A | ENSP00000441802 | ENSP00000358165 | Protocadherin-7; Protocadherin 7. | High affinity immunoglobulin gamma Fc receptor I; High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. | 0.849 |
| PCDH7 | GTPBP1 | ENSP00000441802 | ENSP00000216044 | Protocadherin-7; Protocadherin 7. | GTP-binding protein 1; Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity (By similarity). | 0.829 |
| PCDH7 | GTPBP2 | ENSP00000441802 | ENSP00000303997 | Protocadherin-7; Protocadherin 7. | GTP binding protein 2. | 0.830 |
| PCDH7 | PCDH20-2 | ENSP00000441802 | ENSP00000386653 | Protocadherin-7; Protocadherin 7. | Protocadherin-20; Potential calcium-dependent cell-adhesion protein. | 0.925 |
| PCDH7 | PCDHGB1 | ENSP00000441802 | ENSP00000429273 | Protocadherin-7; Protocadherin 7. | Protocadherin gamma-B1; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. | 0.642 |
| PCDH7 | RRM2 | ENSP00000441802 | ENSP00000353770 | Protocadherin-7; Protocadherin 7. | Ribonucleoside-diphosphate reductase subunit M2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.624 |
| PCDH7 | STIM2 | ENSP00000441802 | ENSP00000417569 | Protocadherin-7; Protocadherin 7. | Stromal interaction molecule 2; Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRA [...] | 0.703 |
| PCDH7 | THSD7A | ENSP00000441802 | ENSP00000406482 | Protocadherin-7; Protocadherin 7. | Thrombospondin type-1 domain-containing protein 7A, soluble form; [Thrombospondin type-1 domain-containing protein 7A]: Plays a role in actin cytoskeleton rearrangement. | 0.676 |
| PCDHGB1 | PCDH20-2 | ENSP00000429273 | ENSP00000386653 | Protocadherin gamma-B1; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. | Protocadherin-20; Potential calcium-dependent cell-adhesion protein. | 0.794 |