Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
POM121L2POM121-like protein 2; POM121 transmembrane nucleoporin like 2; Belongs to the POM121 family. (1035 aa)    
Predicted Functional Partners:
POM121
Nuclear envelope pore membrane protein POM 121; Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL).
     
 
0.900
POM121C
Nuclear envelope pore membrane protein POM 121C; Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL). Belongs to the POM121 family.
     
 
0.900
PRSS16
Thymus-specific serine protease; Protease that may play a role in T-cell development; Belongs to the peptidase S28 family.
      
 0.625
OR14J1
Olfactory receptor 14J1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.515
SLC17A1
Sodium-dependent phosphate transport protein 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Plays a role in urate transport in the kidney.
      
 0.479
ZNF184
Zinc finger protein 184; May be involved in transcriptional regulation.
      
 0.455
GMPPA
Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose.
      
 0.449
PGBD1
piggyBac transposable element derived 1.
      
 0.441
FAM183A
Protein FAM183A; Family with sequence similarity 183 member A; Belongs to the FAM183 family.
      
 0.433
CCDC188
Coiled-coil domain containing 188.
      
 0.425
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.