Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRAMEF10PRAME family member 10; Belongs to the PRAME family. (474 aa)    
Predicted Functional Partners:
PRAMEF17
PRAME family member 17; Belongs to the PRAME family.
  
 
0.999
PRAMEF12
PRAME family member 12; Belongs to the PRAME family.
  
 
0.991
AIP
AH receptor-interacting protein; May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.
    
   0.989
PRAMEF2
PRAME family member 2; Belongs to the PRAME family.
  
 
0.988
PRAMEF1
PRAME family member 1; Belongs to the PRAME family.
  
 
0.988
PRAMEF14
PRAME family member 14.
  
 
0.986
PRAMEF7
PRAME family member 7; Belongs to the PRAME family.
  
 
0.974
PRAMEF8
PRAME family member 8; Belongs to the PRAME family.
  
 
0.972
PRAMEF5
PRAME family member 5; Belongs to the PRAME family.
  
 
0.925
PRAMEF15
PRAME family member 15; Belongs to the PRAME family.
  
 
0.921
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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