PROSER3 protein (human) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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[Homology]

Score

PROSER3

Proline and serine rich 3. (480 aa)

Predicted Functional Partners:

IQCC

0.840

C19orf44

0.558

SCFD2

0.534

PELI3

0.471

CEMIP

0.459

ETNK2

0.455

P3R3URF-PIK3R3

0.440

P3R3URF

0.439

CCDC9B

0.427

ZBTB32

0.426

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C19orf44	PROSER3	ENSP00000221671	ENSP00000380116	Uncharacterized protein C19orf44; Chromosome 19 open reading frame 44.	Proline and serine rich 3.	0.558
CCDC9B	IQCC	ENSP00000453969	ENSP00000442291	Coiled-coil domain containing 9B.	IQ motif containing C.	0.400
CCDC9B	PROSER3	ENSP00000453969	ENSP00000380116	Coiled-coil domain containing 9B.	Proline and serine rich 3.	0.427
CEMIP	PROSER3	ENSP00000378177	ENSP00000380116	Cell migration-inducing and hyaluronan-binding protein; Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tum [...]	Proline and serine rich 3.	0.459
ETNK2	PROSER3	ENSP00000356169	ENSP00000380116	Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity).	Proline and serine rich 3.	0.455
IQCC	CCDC9B	ENSP00000442291	ENSP00000453969	IQ motif containing C.	Coiled-coil domain containing 9B.	0.400
IQCC	PELI3	ENSP00000442291	ENSP00000322532	IQ motif containing C.	E3 ubiquitin-protein ligase pellino homolog 3; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL- 1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation; Belongs to the pellino family.	0.480
IQCC	PROSER3	ENSP00000442291	ENSP00000380116	IQ motif containing C.	Proline and serine rich 3.	0.840
P3R3URF	PROSER3	ENSP00000480059	ENSP00000380116	PIK3R3 upstream reading frame.	Proline and serine rich 3.	0.439
P3R3URF-PIK3R3	PROSER3	ENSP00000439913	ENSP00000380116	Uncharacterized protein.	Proline and serine rich 3.	0.440
PELI3	IQCC	ENSP00000322532	ENSP00000442291	E3 ubiquitin-protein ligase pellino homolog 3; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL- 1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation; Belongs to the pellino family.	IQ motif containing C.	0.480
PELI3	PROSER3	ENSP00000322532	ENSP00000380116	E3 ubiquitin-protein ligase pellino homolog 3; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL- 1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation; Belongs to the pellino family.	Proline and serine rich 3.	0.471
PROSER3	C19orf44	ENSP00000380116	ENSP00000221671	Proline and serine rich 3.	Uncharacterized protein C19orf44; Chromosome 19 open reading frame 44.	0.558
PROSER3	CCDC9B	ENSP00000380116	ENSP00000453969	Proline and serine rich 3.	Coiled-coil domain containing 9B.	0.427
PROSER3	CEMIP	ENSP00000380116	ENSP00000378177	Proline and serine rich 3.	Cell migration-inducing and hyaluronan-binding protein; Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tum [...]	0.459
PROSER3	ETNK2	ENSP00000380116	ENSP00000356169	Proline and serine rich 3.	Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity).	0.455
PROSER3	IQCC	ENSP00000380116	ENSP00000442291	Proline and serine rich 3.	IQ motif containing C.	0.840
PROSER3	P3R3URF	ENSP00000380116	ENSP00000480059	Proline and serine rich 3.	PIK3R3 upstream reading frame.	0.439
PROSER3	P3R3URF-PIK3R3	ENSP00000380116	ENSP00000439913	Proline and serine rich 3.	Uncharacterized protein.	0.440
PROSER3	PELI3	ENSP00000380116	ENSP00000322532	Proline and serine rich 3.	E3 ubiquitin-protein ligase pellino homolog 3; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL- 1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation; Belongs to the pellino family.	0.471