Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
PSG2Pregnancy specific beta-1-glycoprotein 2. (335 aa)    
Predicted Functional Partners:
PSG11
Pregnancy specific beta-1-glycoprotein 11.
  
  
0.935
PSG5
Pregnancy specific beta-1-glycoprotein 5; Belongs to the immunoglobulin superfamily. CEA family.
  
  
0.851
PSG1
Pregnancy specific beta-1-glycoprotein 1; Belongs to the immunoglobulin superfamily. CEA family.
  
  
0.833
PSG3
Pregnancy specific beta-1-glycoprotein 3; Belongs to the immunoglobulin superfamily. CEA family.
  
  
0.785
CSH1
Chorionic somatomammotropin hormone 1; Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization.
   
  
 0.743
CSH2
Chorionic somatomammotropin hormone 2; Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization.
   
  
 0.742
PSG6
Pregnancy specific beta-1-glycoprotein 6.
  
  
0.740
PSG4
Pregnancy specific beta-1-glycoprotein 4.
  
  
0.738
PSG7
Pregnancy specific beta-1-glycoprotein 7.
  
  
0.651
TGFB1
Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]
   
 
 0.630
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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