RGPD3 protein (human) - STRING interaction network

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Score

RGPD3

RANBP2 like and GRIP domain containing 3. (1758 aa)

Predicted Functional Partners:

RANBP2

0.990

RGPD1

0.990

RGPD8

0.989

RGPD4

0.989

RGPD6

0.988

RGPD2

0.976

RCC1

0.951

NUP93

0.916

NUP98

0.901

NUP133

0.869

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NUP133	NUP93	ENSP00000261396	ENSP00000310668	Nuclear pore complex protein Nup133; Involved in poly(A)+ RNA transport. Involved in nephrogenesis.	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.	0.998
NUP133	NUP98	ENSP00000261396	ENSP00000316032	Nuclear pore complex protein Nup133; Involved in poly(A)+ RNA transport. Involved in nephrogenesis.	Nuclear pore complex protein Nup98-Nup96; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. NUP98 and NUP96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC. In cooperation with DHX9, plays a role in transcription and alternative splicing activation of a subset of genes. Involved in the localization of DHX9 in discrete intranuclear foci (GLFG-body).	0.999
NUP133	RANBP2	ENSP00000261396	ENSP00000283195	Nuclear pore complex protein Nup133; Involved in poly(A)+ RNA transport. Involved in nephrogenesis.	E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Binds single-stranded RNA (in vitro). May bind DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex [...]	0.998
NUP133	RCC1	ENSP00000261396	ENSP00000497402	Nuclear pore complex protein Nup133; Involved in poly(A)+ RNA transport. Involved in nephrogenesis.	Regulator of chromosome condensation; Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis. Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import. Involved in the regulation of onset of chromoso [...]	0.439
NUP133	RGPD2	ENSP00000261396	ENSP00000381214	Nuclear pore complex protein Nup133; Involved in poly(A)+ RNA transport. Involved in nephrogenesis.	RANBP2 like and GRIP domain containing 2.	0.741
NUP133	RGPD3	ENSP00000261396	ENSP00000386588	Nuclear pore complex protein Nup133; Involved in poly(A)+ RNA transport. Involved in nephrogenesis.	RANBP2 like and GRIP domain containing 3.	0.869
NUP133	RGPD4	ENSP00000261396	ENSP00000386810	Nuclear pore complex protein Nup133; Involved in poly(A)+ RNA transport. Involved in nephrogenesis.	RANBP2 like and GRIP domain containing 4.	0.820
NUP133	RGPD6	ENSP00000261396	ENSP00000330842	Nuclear pore complex protein Nup133; Involved in poly(A)+ RNA transport. Involved in nephrogenesis.	RANBP2 like and GRIP domain containing 6.	0.865
NUP133	RGPD8	ENSP00000261396	ENSP00000306637	Nuclear pore complex protein Nup133; Involved in poly(A)+ RNA transport. Involved in nephrogenesis.	RANBP2 like and GRIP domain containing 8.	0.817
NUP93	NUP133	ENSP00000310668	ENSP00000261396	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.	Nuclear pore complex protein Nup133; Involved in poly(A)+ RNA transport. Involved in nephrogenesis.	0.998
NUP93	NUP98	ENSP00000310668	ENSP00000316032	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.	Nuclear pore complex protein Nup98-Nup96; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. NUP98 and NUP96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC. In cooperation with DHX9, plays a role in transcription and alternative splicing activation of a subset of genes. Involved in the localization of DHX9 in discrete intranuclear foci (GLFG-body).	0.998
NUP93	RANBP2	ENSP00000310668	ENSP00000283195	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.	E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Binds single-stranded RNA (in vitro). May bind DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex [...]	0.998
NUP93	RCC1	ENSP00000310668	ENSP00000497402	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.	Regulator of chromosome condensation; Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis. Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import. Involved in the regulation of onset of chromoso [...]	0.598
NUP93	RGPD2	ENSP00000310668	ENSP00000381214	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.	RANBP2 like and GRIP domain containing 2.	0.725
NUP93	RGPD3	ENSP00000310668	ENSP00000386588	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.	RANBP2 like and GRIP domain containing 3.	0.916
NUP93	RGPD4	ENSP00000310668	ENSP00000386810	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.	RANBP2 like and GRIP domain containing 4.	0.838
NUP93	RGPD6	ENSP00000310668	ENSP00000330842	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.	RANBP2 like and GRIP domain containing 6.	0.914
NUP93	RGPD8	ENSP00000310668	ENSP00000306637	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.	RANBP2 like and GRIP domain containing 8.	0.831
NUP98	NUP133	ENSP00000316032	ENSP00000261396	Nuclear pore complex protein Nup98-Nup96; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. NUP98 and NUP96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC. In cooperation with DHX9, plays a role in transcription and alternative splicing activation of a subset of genes. Involved in the localization of DHX9 in discrete intranuclear foci (GLFG-body).	Nuclear pore complex protein Nup133; Involved in poly(A)+ RNA transport. Involved in nephrogenesis.	0.999
NUP98	NUP93	ENSP00000316032	ENSP00000310668	Nuclear pore complex protein Nup98-Nup96; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. NUP98 and NUP96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC. In cooperation with DHX9, plays a role in transcription and alternative splicing activation of a subset of genes. Involved in the localization of DHX9 in discrete intranuclear foci (GLFG-body).	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.	0.998