Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RTL9Retrotransposon Gag like 9. (1388 aa)    
Predicted Functional Partners:
RTL6
Retrotransposon Gag like 6.
      
 0.782
LDOC1
Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.
  
  
 0.779
RTL8C
Retrotransposon Gag like 8C; Belongs to the FAM127 family.
   
  
 0.763
RTL4
Retrotransposon Gag-like protein 4; Involved in cognitive function in the brain, possibly via the noradrenergic system.
   
  
 0.703
AMMECR1
AMMECR nuclear protein 1.
   
  
 0.607
NUTM2G
NUT family member 2G.
      
 0.579
PNMA6F
Paraneoplastic antigen Ma6F; PNMA family member 6F.
    
 
 0.574
TMEM164
Transmembrane protein 164; Belongs to the TMEM164 family.
   
  
 0.551
RTL8A
Retrotransposon Gag like 8A; Belongs to the FAM127 family.
      
 0.547
CBX6
Chromobox protein homolog 6; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin. Recruitment to chromatin might occur in an H3K27me3- in [...]
    
   0.507
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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