Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLC25A43Solute carrier family 25 member 43; Belongs to the mitochondrial carrier (TC 2.A.29) family. (341 aa)    
Predicted Functional Partners:
SLC25A53
Solute carrier family 25 member 53.
   
  
 0.663
FAU
Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.
   
   0.652
RPL14
60S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family.
   
 
 0.608
CXorf56
UPF0428 protein CXorf56; Chromosome X open reading frame 56.
   
  
 0.599
PROSER2
Proline and serine rich 2.
   
   0.574
RPL6
60S ribosomal protein L6; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL6 family.
   
 
 0.560
RPL4
Ribosomal protein L4.
   
 
 0.557
RPL8
60S ribosomal protein L8; Component of the large ribosomal subunit.
   
 
 0.540
RPS18
40S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.
   
 
 0.539
RPL13
Ribosomal protein L13.
   
 
 0.532
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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