| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ELAVL1 | SOX12 | ENSP00000385269 | ENSP00000347646 | ELAV-like protein 1; RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability. Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation (By similarity). Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA, and AUUUUU [...] | Transcription factor SOX-12; Binds to the sequence 5'-AACAAT-3'. | 0.528 |
| ELAVL1 | ZRANB1 | ENSP00000385269 | ENSP00000352676 | ELAV-like protein 1; RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability. Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation (By similarity). Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA, and AUUUUU [...] | Ubiquitin thioesterase ZRANB1; Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling; Belongs to the peptidase C64 family. | 0.463 |
| GYG1 | GYS1 | ENSP00000340736 | ENSP00000317904 | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | Glycogen [starch] synthase, muscle; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. | 0.999 |
| GYG1 | SOX12 | ENSP00000340736 | ENSP00000347646 | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | Transcription factor SOX-12; Binds to the sequence 5'-AACAAT-3'. | 0.973 |
| GYS1 | GYG1 | ENSP00000317904 | ENSP00000340736 | Glycogen [starch] synthase, muscle; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | 0.999 |
| GYS1 | SOX12 | ENSP00000317904 | ENSP00000347646 | Glycogen [starch] synthase, muscle; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. | Transcription factor SOX-12; Binds to the sequence 5'-AACAAT-3'. | 0.999 |
| NRSN2 | SOX12 | ENSP00000371728 | ENSP00000347646 | Neurensin-2; May play a role in maintenance and/or transport of vesicles; Belongs to the VMP family. | Transcription factor SOX-12; Binds to the sequence 5'-AACAAT-3'. | 0.445 |
| SOX12 | ELAVL1 | ENSP00000347646 | ENSP00000385269 | Transcription factor SOX-12; Binds to the sequence 5'-AACAAT-3'. | ELAV-like protein 1; RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability. Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation (By similarity). Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA, and AUUUUU [...] | 0.528 |
| SOX12 | GYG1 | ENSP00000347646 | ENSP00000340736 | Transcription factor SOX-12; Binds to the sequence 5'-AACAAT-3'. | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | 0.973 |
| SOX12 | GYS1 | ENSP00000347646 | ENSP00000317904 | Transcription factor SOX-12; Binds to the sequence 5'-AACAAT-3'. | Glycogen [starch] synthase, muscle; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. | 0.999 |
| SOX12 | NRSN2 | ENSP00000347646 | ENSP00000371728 | Transcription factor SOX-12; Binds to the sequence 5'-AACAAT-3'. | Neurensin-2; May play a role in maintenance and/or transport of vesicles; Belongs to the VMP family. | 0.445 |
| SOX12 | ZRANB1 | ENSP00000347646 | ENSP00000352676 | Transcription factor SOX-12; Binds to the sequence 5'-AACAAT-3'. | Ubiquitin thioesterase ZRANB1; Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling; Belongs to the peptidase C64 family. | 0.457 |
| ZRANB1 | ELAVL1 | ENSP00000352676 | ENSP00000385269 | Ubiquitin thioesterase ZRANB1; Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling; Belongs to the peptidase C64 family. | ELAV-like protein 1; RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability. Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation (By similarity). Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA, and AUUUUU [...] | 0.463 |
| ZRANB1 | SOX12 | ENSP00000352676 | ENSP00000347646 | Ubiquitin thioesterase ZRANB1; Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling; Belongs to the peptidase C64 family. | Transcription factor SOX-12; Binds to the sequence 5'-AACAAT-3'. | 0.457 |