Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPANXN4Sperm protein associated with the nucleus on the X chromosome N4; SPANX family member N4; Belongs to the SPAN-X family. (99 aa)    
Predicted Functional Partners:
SPANXA2
Sperm protein associated with the nucleus on the X chromosome A; SPANX family member A2; Belongs to the SPAN-X family.
   
  
 0.921
SPANXA1
Sperm protein associated with the nucleus, X-linked, family member A1.
   
  
 0.880
SPANXD
Sperm protein associated with the nucleus on the X chromosome D; SPANX family member D; Belongs to the SPAN-X family.
   
  
 0.619
CSAG3
Chondrosarcoma-associated gene 2/3 protein; Drug-resistance related protein, its expression is associated with the chemotherapy resistant and neoplastic phenotype. May also be linked to the malignant phenotype.
    
 
 0.594
TENT5D
Terminal nucleotidyltransferase 5D; Nucleotidyltransferase that act as a non-canonical poly(A) RNA polymerase; Belongs to the TENT family.
      
 0.559
CXorf51A
Uncharacterized protein CXorf51A; Chromosome X open reading frame 51A.
      
 0.539
FAM133A
Protein FAM133A; Family with sequence similarity 133 member A.
      
 0.526
CXorf40B
Protein CXorf40B.
      
 0.498
XAGE3
X antigen family member 3.
      
 0.497
SRPK1
SRSF protein kinase 1; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Plays a central role in the regulatory network for splicing, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis. Can influence additional steps of mRNA maturation, as well as other cellular activiti [...]
    
   0.457
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.