| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LCE3E | SPRR1A | ENSP00000357778 | ENSP00000357751 | Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum. | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | 0.717 |
| LCE3E | SPRR1B | ENSP00000357778 | ENSP00000306461 | Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum. | Cornifin-B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage; Belongs to the cornifin (SPRR) family. | 0.714 |
| LCE3E | SPRR2A | ENSP00000357778 | ENSP00000376423 | Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum. | Small proline rich protein 2A. | 0.769 |
| LCE3E | SPRR2B | ENSP00000357778 | ENSP00000357744 | Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum. | Small proline-rich protein 2A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Belongs to the cornifin (SPRR) family. | 0.883 |
| LCE3E | SPRR2D | ENSP00000357778 | ENSP00000357746 | Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum. | Small proline-rich protein 2D; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | 0.827 |
| LCE3E | SPRR2E | ENSP00000357778 | ENSP00000357740 | Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum. | Small proline-rich protein 2E; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | 0.865 |
| LCE3E | SPRR2F | ENSP00000357778 | ENSP00000418193 | Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum. | Small proline-rich protein 2F; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). | 0.768 |
| LCE3E | SPRR2G | ENSP00000357778 | ENSP00000357737 | Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum. | Small proline-rich protein 2G; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). | 0.884 |
| LCE3E | SPRR3 | ENSP00000357778 | ENSP00000330391 | Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum. | Small proline-rich protein 3; Cross-linked envelope protein of keratinocytes. | 0.738 |
| LCE3E | SPRR4 | ENSP00000357778 | ENSP00000332163 | Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum. | Small proline-rich protein 4; Cross-linked envelope protein of keratinocytes. Involved in UV-induced cornification; Belongs to the cornifin (SPRR) family. | 0.504 |
| SPRR1A | LCE3E | ENSP00000357751 | ENSP00000357778 | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum. | 0.717 |
| SPRR1A | SPRR1B | ENSP00000357751 | ENSP00000306461 | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | Cornifin-B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage; Belongs to the cornifin (SPRR) family. | 0.997 |
| SPRR1A | SPRR2A | ENSP00000357751 | ENSP00000376423 | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | Small proline rich protein 2A. | 0.884 |
| SPRR1A | SPRR2B | ENSP00000357751 | ENSP00000357744 | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | Small proline-rich protein 2A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Belongs to the cornifin (SPRR) family. | 0.988 |
| SPRR1A | SPRR2D | ENSP00000357751 | ENSP00000357746 | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | Small proline-rich protein 2D; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | 0.965 |
| SPRR1A | SPRR2E | ENSP00000357751 | ENSP00000357740 | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | Small proline-rich protein 2E; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | 0.966 |
| SPRR1A | SPRR2F | ENSP00000357751 | ENSP00000418193 | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | Small proline-rich protein 2F; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). | 0.949 |
| SPRR1A | SPRR2G | ENSP00000357751 | ENSP00000357737 | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | Small proline-rich protein 2G; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). | 0.766 |
| SPRR1A | SPRR3 | ENSP00000357751 | ENSP00000330391 | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | Small proline-rich protein 3; Cross-linked envelope protein of keratinocytes. | 0.985 |
| SPRR1A | SPRR4 | ENSP00000357751 | ENSP00000332163 | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | Small proline-rich protein 4; Cross-linked envelope protein of keratinocytes. Involved in UV-induced cornification; Belongs to the cornifin (SPRR) family. | 0.947 |