Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSX3Protein SSX3; Could act as a modulator of transcription; Belongs to the SSX family. (188 aa)    
Predicted Functional Partners:
SSX2
SSX family member 2.
   
 
0.988
SSX7
Protein SSX7; Could act as a modulator of transcription; Belongs to the SSX family.
   
 
0.952
SSX1
Protein SSX1; Could act as a modulator of transcription; Belongs to the SSX family.
   
 
0.920
SSX2B
SSX family member 2B.
   
  
0.914
SSX4
Protein SSX4; Could act as a modulator of transcription.
   
 
0.836
SSX2IP
Afadin- and alpha-actinin-binding protein; Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin- catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha- actinin (By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via [...]
    
 
 0.830
SSX4B
SSX family member 4B.
   
 
0.828
MIPOL1
Mirror-image polydactyly 1.
    
   0.809
SS18
Protein SSXT; Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner.
      
 0.697
CDR2
Cerebellar degeneration related protein 2.
    
   0.685
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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