TCP11L2 protein (human) - STRING interaction network

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TCP11L2

T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. (519 aa)

Predicted Functional Partners:

TUBA1B

0.977

TUBA1C

0.961

TUBA4A

0.883

TUBA1A

0.879

TTC5

0.841

TUBA3E

0.779

TUBAL3

0.663

TMEM263

0.605

TUBA3D

0.598

POLR3B

0.576

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
POLR3B	TCP11L2	ENSP00000228347	ENSP00000299045	DNA-directed RNA polymerase III subunit RPC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the clef [...]	T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family.	0.576
POLR3B	TMEM263	ENSP00000228347	ENSP00000449785	DNA-directed RNA polymerase III subunit RPC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the clef [...]	Transmembrane protein 263.	0.517
POLR3B	TTC5	ENSP00000228347	ENSP00000258821	DNA-directed RNA polymerase III subunit RPC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the clef [...]	Tetratricopeptide repeat protein 5; Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).	0.513
TCP11L2	POLR3B	ENSP00000299045	ENSP00000228347	T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family.	DNA-directed RNA polymerase III subunit RPC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the clef [...]	0.576
TCP11L2	TMEM263	ENSP00000299045	ENSP00000449785	T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family.	Transmembrane protein 263.	0.605
TCP11L2	TTC5	ENSP00000299045	ENSP00000258821	T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family.	Tetratricopeptide repeat protein 5; Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).	0.841
TCP11L2	TUBA1A	ENSP00000299045	ENSP00000439020	T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family.	Detyrosinated tubulin alpha-1A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.879
TCP11L2	TUBA1B	ENSP00000299045	ENSP00000336799	T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family.	Detyrosinated tubulin alpha-1B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.977
TCP11L2	TUBA1C	ENSP00000299045	ENSP00000443475	T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family.	Detyrosinated tubulin alpha-1C chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family.	0.961
TCP11L2	TUBA3D	ENSP00000299045	ENSP00000326042	T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family.	Detyrosinated tubulin alpha-3C chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.598
TCP11L2	TUBA3E	ENSP00000299045	ENSP00000318197	T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family.	Detyrosinated tubulin alpha-3E chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). Belongs to the tubulin family.	0.779
TCP11L2	TUBA4A	ENSP00000299045	ENSP00000248437	T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family.	Tubulin alpha-4A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.883
TCP11L2	TUBAL3	ENSP00000299045	ENSP00000369784	T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family.	Tubulin alpha chain-like 3; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). Belongs to the tubulin family.	0.663
TMEM263	POLR3B	ENSP00000449785	ENSP00000228347	Transmembrane protein 263.	DNA-directed RNA polymerase III subunit RPC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the clef [...]	0.517
TMEM263	TCP11L2	ENSP00000449785	ENSP00000299045	Transmembrane protein 263.	T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family.	0.605
TTC5	POLR3B	ENSP00000258821	ENSP00000228347	Tetratricopeptide repeat protein 5; Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).	DNA-directed RNA polymerase III subunit RPC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the clef [...]	0.513
TTC5	TCP11L2	ENSP00000258821	ENSP00000299045	Tetratricopeptide repeat protein 5; Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).	T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family.	0.841
TTC5	TUBA1A	ENSP00000258821	ENSP00000439020	Tetratricopeptide repeat protein 5; Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).	Detyrosinated tubulin alpha-1A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.539
TTC5	TUBA1C	ENSP00000258821	ENSP00000443475	Tetratricopeptide repeat protein 5; Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).	Detyrosinated tubulin alpha-1C chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family.	0.774
TUBA1A	TCP11L2	ENSP00000439020	ENSP00000299045	Detyrosinated tubulin alpha-1A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family.	0.879