Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TMEM213Transmembrane protein 213. (107 aa)    
Predicted Functional Partners:
ATP6V0A4
V-type proton ATPase 116 kDa subunit a isoform 4; Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney.
   
  
 0.588
TMEM207
Transmembrane protein 207.
   
  
 0.587
TMEM116
Transmembrane protein 116.
   
  
 0.585
MAT2A
S-adenosylmethionine synthase isoform type-2; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate; Belongs to the AdoMet synthase family.
    
   0.562
TMEM72
Transmembrane protein 72.
   
  
 0.516
RTP3
Receptor-transporting protein 3; Promotes functional cell surface expression of the bitter taste receptors TAS2R16 and TAS2R43; Belongs to the TMEM7 family.
      
 0.468
TMEM61
Transmembrane protein 61.
   
  
 0.460
PLEKHG7
Pleckstrin homology and RhoGEF domain containing G7.
   
  
 0.460
CDC20B
Cell division cycle 20B; Belongs to the WD repeat CDC20/Fizzy family.
   
    0.447
TMEM25
Transmembrane protein 25; In neurons, modulates the degradation of NMDA receptor GRIN2B subunit. Plays a role in the regulation of neuronal excitability.
      
 0.441
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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