| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANKK1 | DRD2 | ENSP00000306678 | ENSP00000354859 | Ankyrin repeat and kinase domain containing 1. | D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | 0.957 |
| ANKK1 | TTC12 | ENSP00000306678 | ENSP00000419652 | Ankyrin repeat and kinase domain containing 1. | Tetratricopeptide repeat domain 12. | 0.947 |
| CFAP43 | CFAP44 | ENSP00000349568 | ENSP00000377428 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function. | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | 0.991 |
| CFAP43 | DNAH1 | ENSP00000349568 | ENSP00000401514 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function. | Dynein heavy chain 1, axonemal; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme ; Belongs to the dynein heavy chain family. | 0.993 |
| CFAP43 | DNAI1 | ENSP00000349568 | ENSP00000480538 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function. | Dynein intermediate chain 1, axonemal; Part of the dynein complex of respiratory cilia; Belongs to the dynein intermediate chain family. | 0.928 |
| CFAP43 | GAS8 | ENSP00000349568 | ENSP00000268699 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function. | Dynein regulatory complex subunit 4; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays an important role in the assembly of the N-DRC linker (By similarity). Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper motile cilia functioning. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh [...] | 0.925 |
| CFAP43 | NME8 | ENSP00000349568 | ENSP00000199447 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function. | Thioredoxin domain-containing protein 3; Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds. | 0.724 |
| CFAP43 | RSPH1 | ENSP00000349568 | ENSP00000291536 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function. | Radial spoke head 1 homolog; May play an important role in male meiosis (By similarity). It is necessary for proper building of the axonemal central pair and radial spokes. | 0.916 |
| CFAP43 | TTC12 | ENSP00000349568 | ENSP00000419652 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function. | Tetratricopeptide repeat domain 12. | 0.581 |
| CFAP44 | CFAP43 | ENSP00000377428 | ENSP00000349568 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function. | 0.991 |
| CFAP44 | DNAH1 | ENSP00000377428 | ENSP00000401514 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Dynein heavy chain 1, axonemal; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme ; Belongs to the dynein heavy chain family. | 0.973 |
| CFAP44 | DNAI1 | ENSP00000377428 | ENSP00000480538 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Dynein intermediate chain 1, axonemal; Part of the dynein complex of respiratory cilia; Belongs to the dynein intermediate chain family. | 0.920 |
| CFAP44 | GAS8 | ENSP00000377428 | ENSP00000268699 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Dynein regulatory complex subunit 4; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays an important role in the assembly of the N-DRC linker (By similarity). Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper motile cilia functioning. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh [...] | 0.922 |
| CFAP44 | NME8 | ENSP00000377428 | ENSP00000199447 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Thioredoxin domain-containing protein 3; Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds. | 0.545 |
| CFAP44 | RSPH1 | ENSP00000377428 | ENSP00000291536 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Radial spoke head 1 homolog; May play an important role in male meiosis (By similarity). It is necessary for proper building of the axonemal central pair and radial spokes. | 0.901 |
| CFAP44 | TTC12 | ENSP00000377428 | ENSP00000419652 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Tetratricopeptide repeat domain 12. | 0.565 |
| DNAH1 | CFAP43 | ENSP00000401514 | ENSP00000349568 | Dynein heavy chain 1, axonemal; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme ; Belongs to the dynein heavy chain family. | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function. | 0.993 |
| DNAH1 | CFAP44 | ENSP00000401514 | ENSP00000377428 | Dynein heavy chain 1, axonemal; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme ; Belongs to the dynein heavy chain family. | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | 0.973 |
| DNAH1 | DNAI1 | ENSP00000401514 | ENSP00000480538 | Dynein heavy chain 1, axonemal; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme ; Belongs to the dynein heavy chain family. | Dynein intermediate chain 1, axonemal; Part of the dynein complex of respiratory cilia; Belongs to the dynein intermediate chain family. | 0.976 |
| DNAH1 | GAS8 | ENSP00000401514 | ENSP00000268699 | Dynein heavy chain 1, axonemal; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme ; Belongs to the dynein heavy chain family. | Dynein regulatory complex subunit 4; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays an important role in the assembly of the N-DRC linker (By similarity). Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper motile cilia functioning. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh [...] | 0.946 |