Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
VCX2Variable charge X-linked protein 2; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Belongs to the VCX/VCY family. (139 aa)    
Predicted Functional Partners:
VCX3A
Variable charge X-linked protein 3; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Belongs to the VCX/VCY family.
   
  
0.947
VCX
Variable charge X-linked protein 1; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Belongs to the VCX/VCY family.
   
  
0.946
VCX3B
Variable charge X-linked protein 3B; May mediate a process in spermatogenesis or may play a role in sex ratio distortion.
   
  
0.944
STS
Steryl-sulfatase; Catalyzes the conversion of sulfated steroid precursors, such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate to the free steroid.
      
 0.802
PUDP
Pseudouridine-5'-phosphatase; Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine; Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
      
 0.716
PNPLA4
Patatin-like phospholipase domain-containing protein 4; Lipid hydrolase.
      
 0.715
ARX
Homeobox protein ARX; Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate; Belongs to the paired homeobox family. Bicoid subfamily.
      
 0.660
HSFX2
Heat shock transcription factor family, X-linked 2.
      
 0.538
FAM9B
Protein FAM9B; Family with sequence similarity 9 member B; Belongs to the FAM9 family.
      
 0.535
FAM9A
Protein FAM9A; Family with sequence similarity 9 member A.
      
 0.494
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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