Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
Databases
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[Homology]
Score
VCX3BVariable charge X-linked protein 3B; May mediate a process in spermatogenesis or may play a role in sex ratio distortion. (246 aa)    
Predicted Functional Partners:
VCX
Variable charge X-linked protein 1; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Belongs to the VCX/VCY family.
  
  
0.955
VCX3A
Variable charge X-linked protein 3; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Belongs to the VCX/VCY family.
  
  
0.955
VCX2
Variable charge X-linked protein 2; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Belongs to the VCX/VCY family.
   
  
0.944
ARX
Homeobox protein ARX; Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate; Belongs to the paired homeobox family. Bicoid subfamily.
    
 
 0.667
PUDP
Pseudouridine-5'-phosphatase; Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine; Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
   
  
 0.624
PNPLA4
Patatin-like phospholipase domain-containing protein 4; Lipid hydrolase.
      
 0.600
HSFX2
Heat shock transcription factor family, X-linked 2.
      
 0.568
STS
Steryl-sulfatase; Catalyzes the conversion of sulfated steroid precursors, such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate to the free steroid.
      
 0.510
FAM9B
Protein FAM9B; Family with sequence similarity 9 member B; Belongs to the FAM9 family.
      
 0.494
HSFX1
Heat shock transcription factor family, X-linked 1.
      
 0.489
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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