Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
WFDC10BProtein WFDC10B; WAP four-disulfide core domain 10B. (89 aa)    
Predicted Functional Partners:
WFDC3
WAP four-disulfide core domain 3.
   
  
 0.716
WFDC13
WAP four-disulfide core domain protein 13; Putative acid-stable proteinase inhibitor.
   
  
 0.629
MS4A5
Membrane-spanning 4-domains subfamily A member 5; May be involved in signal transduction as a component of a multimeric receptor complex.
   
  
 0.605
SPINT4
Serine peptidase inhibitor, Kunitz type 4.
   
  
 0.591
SPATA25
Spermatogenesis-associated protein 25; May play a role in spermatogenesis. Belongs to the SPATA25 family.
   
  
 0.580
CT62
Cancer/testis associated 62.
   
    0.558
GPR152
Probable G-protein coupled receptor 152; Orphan receptor.
   
    0.554
GYPE
Glycophorin-E; This protein is a minor sialoglycoprotein in human erythrocyte membranes; Belongs to the glycophorin-A family.
   
    0.550
ZSWIM1
Zinc finger SWIM-type containing 1.
      
 0.548
C11orf45
Putative uncharacterized protein C11orf45; Chromosome 11 open reading frame 45.
   
    0.533
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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